000			03312nam a22005175i 4500
001			u374686
003			SIRSI
005			20160812084247.0
007			cr nn 008mamaa
008			140417s2010 gw | s |||| 0|eng d
020			_a9783642141539 _9978-3-642-14153-9
040			_cMX-MeUAM
050		4	_aRB155-155.8
050		4	_aQH431
082	0	4	_a611.01816 _223
082	0	4	_a599.935 _223
100	1		_aMartin, Roland. _eeditor.
245	1	0	_aMolecular Basis of Multiple Sclerosis _h[recurso electrónico] : _bThe Immune System / _cedited by Roland Martin, Andreas Lutterotti.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2010.
300			_aVIII, 308 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aResults and Problems in Cell Differentiation, _x0080-1844 ; _v51
505	0		_aThe Genetics of Multiple Sclerosis -- Potential Triggers of MS -- Immunological Basis for the Development of Tissue Inflammation and Organ-Specific Autoimmunity in Animal Models of Multiple Sclerosis -- T-Cells in Multiple Sclerosis -- B Cells and Antibodies in MS -- Cooperation of B Cells and T Cells in the Pathogenesis of Multiple Sclerosis -- Role of NK Cells and Invariant NKT Cells in Multiple Sclerosis -- Antigen Processing and Presentation in Multiple Sclerosis -- Immune-Mediated CNS Damage -- Neuro-Immune Crosstalk in CNS Diseases -- Prospects for Antigen-Specific Tolerance Based Therapies for the Treatment of Multiple Sclerosis -- Immuno-Therapeutic Potential of Haematopoietic and Mesenchymal Stem Cell Transplantation in MS -- Multiple Sclerosis Therapies: Molecular Mechanisms and Future -- Examination of the Role of MRI in Multiple Sclerosis: A Problem Orientated Approach.
520			_aDespite major efforts by the scientific community over the years, our understanding of the pathogenesis or the mechanisms of injury of multiple sclerosis is still limited. Consequently, the current strategies for treatment and management of patients are limited in their efficacy. The mechanisms of tissue protection and repair are probably even less understood. One reason for these limitations is the enormous complexity of the disease and every facet of its pathogenesis, the mechanisms of tissue injury, the diagnostic procedures and finally the efficacy of treatments and their side effects. The aim of this book is to review the most recent advances made in this highly complex field.
650		0	_aMedicine.
650		0	_aHuman genetics.
650		0	_aImmunology.
650		0	_aCytology.
650	1	4	_aBiomedicine.
650	2	4	_aHuman Genetics.
650	2	4	_aCell Biology.
650	2	4	_aMolecular Medicine.
650	2	4	_aImmunology.
700	1		_aLutterotti, Andreas. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783642141522
830		0	_aResults and Problems in Cell Differentiation, _x0080-1844 ; _v51
856	4	0	_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-3-642-14153-9
596			_a19
942			_cLIBRO_ELEC
999			_c202566 _d202566