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005 | 20160812084250.0 | ||
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008 | 101109s2011 gw | s |||| 0|eng d | ||
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_a9783642144295 _9978-3-642-14429-5 |
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040 | _cMX-MeUAM | ||
050 | 4 | _aQR180-189.5 | |
082 | 0 | 4 |
_a616.079 _223 |
100 | 1 |
_aBalogh, Peter. _eeditor. |
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245 | 1 | 0 |
_aDevelopmental Biology of Peripheral Lymphoid Organs _h[recurso electrónico] / _cedited by Peter Balogh. |
264 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2011. |
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300 |
_aX, 177 p. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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505 | 0 | _aIntroduction: Evolution of peripheral lymphoid organs -- Common themes in lymphoid organ development -- Development of lymph nodes in humans and rodents -- Programmed and nascent gut-associated organized lymphoid tissues -- Single complexity: the spleen -- Age-associated decline in peripheral lymphoid organ functions. | |
520 | _aThe human immune system is a complex network of tissues and organs dispersed throughout the body. Immunology, as one of the most rapidly evolving fields in biomedical research, has to date covered the essential cellular and molecular events necessary for immune responses to occur, but has paid relatively little attention to important developmental processes underlying the formation of the tissues themselves that carry out immune responses in humans and other mammalians. In contrast to the thymus and bone marrow that generate mature leukocytes for antigen recognition and handling, these latter tissues display broad tissue distribution and possess diverse architectural characteristics. These peripheral lymphoid tissues and organs develop prior to the individual’s exposure to external antigens, and despite their similar functions, their varied appearances indicate a substantial complexity of tissue ontogeny. This volume presents a comprehensive overview of the developmental features of the major peripheral lymphoid organs, thus examining the connection between immunological functionality and structural characteristics utilizing a developmental approach, for an audience ranging from undergraduate students to senior researchers in immunology, histology and clinical medicine. | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aHuman physiology. | |
650 | 0 | _aImmunology. | |
650 | 0 | _aDevelopmental biology. | |
650 | 1 | 4 | _aBiomedicine. |
650 | 2 | 4 | _aImmunology. |
650 | 2 | 4 | _aDevelopmental Biology. |
650 | 2 | 4 | _aHuman Physiology. |
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9783642144288 |
856 | 4 | 0 |
_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-3-642-14429-5 |
596 | _a19 | ||
942 | _cLIBRO_ELEC | ||
999 |
_c202639 _d202639 |