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020 _a9783642181207
_9978-3-642-18120-7
040 _cMX-MeUAM
050 4 _aRC321-580
082 0 4 _a612.8
_223
100 1 _aAngelov, Doychin N.
_eauthor.
245 1 0 _aPhysical Rehabilitation of Paralysed Facial Muscles: Functional and Morphological Correlates
_h[recurso electrónico] /
_cby Doychin N. Angelov.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2011.
300 _aXII, 143p. 22 illus., 14 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Anatomy, Embryology and Cell Biology,
_x0301-5556 ;
_v210
505 0 _aFactors limiting motor recovery after peripheral nerve injury -- Attempts to improve axonal pathfinding and quality of target reinnervation -- Efforts to reduce collateral axonal branching at the lesion site -- Efforts to reduce intramuscular axonal sprouting in denervated muscles -- Discussion -- Significance axonal branching at the lesion site -- Unsuccessful ways to reduce intramuscular axonal sprouting in denerved muscles -- Successful ways to reduce intramuscular axonal sprouting in paralysed muscles -- Unsuccessful manual stimulation of paralysed forearm muscles after MMA -- Conclusions -- Subject index.
520 _aUsing a combined morpho-functional approach the author found that polyinnervation of the neuro-muscular juction (NMJ) is the critical factor for recovery of function after transection and suture of the facial nerve. Since polyinnervation is activity-dependent and can be manipulated, the author tried to design a clinically feasible therapy by electrical stimulation or by soft tissue massage. First, electrical stimulation was applied to the transected facial nerve or to paralysed facial muscles. Both procedures did not improve vibrissal motor performance (video-based motion analysis of whisking), failed to diminish polyinnervation and even reduced the number of innervated NMJ to one fifth of normal values. In contrast, gentle stroking of the paralysed vibrissal muscles by hand resulted in full recovery of whisking. This manual stimulation depends on intact sensory supply of the denervated muscle targets and is also effective after hypoglossal-facial anastomosis, after interpositional nerve grafting, when applied to the orbicularis oculi muscle and after transection and suture of the hypoglossal nerve. From these results the author concludes that manual stimulation is a non-invasive procedure with immediate potential for clinical rehabilitation following facial nerve reconstruction.
650 0 _aMedicine.
650 0 _aNeurosciences.
650 1 4 _aBiomedicine.
650 2 4 _aNeurosciences.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642181191
830 0 _aAdvances in Anatomy, Embryology and Cell Biology,
_x0301-5556 ;
_v210
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-3-642-18120-7
596 _a19
942 _cLIBRO_ELEC
999 _c203551
_d203551