000 04020nam a22005295i 4500
001 u375725
003 SIRSI
005 20160812084338.0
007 cr nn 008mamaa
008 110414s2011 gw | s |||| 0|eng d
020 _a9783642183843
_9978-3-642-18384-3
040 _cMX-MeUAM
050 4 _aGE1-350
082 0 4 _a577.14
_223
100 1 _aBrack, Werner.
_eeditor.
245 1 0 _aEffect-Directed Analysis of Complex Environmental Contamination
_h[recurso electrónico] /
_cedited by Werner Brack.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2011.
300 _aXVIII, 346 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aThe Handbook of Environmental Chemistry,
_x1867-979X ;
_v15
505 0 _aEarly Evolution of the Toxicity Identification Evaluation Process: Contributions from the United States Environmental Protection Agency Effluent Testing Program -- Recent Developments in Whole Sediment Toxicity Identification Evaluations: Innovations in Manipulations and Endpoints.-Considerations for Incorporating Bioavailability in EDA and Toxicity Identification Evaluation -- Diagnostic tools for EDA of mutagens, AhR agonists and endocrine disruptors -- Separation Techniques in EDA -- Simultaneous screening and chemical characterization of bioactive compounds using LC-MS based technologies -- Advanced GC-MS and LC-MS tools for structure elucidation in effect-directed analysis -- Computer Tools for Structure Elucidation in EDA -- EDA of mutagens in ambient airborne particles -- EDA of endocrine disruptors in aquatic ecosystems -- ED studies of pulp and paper mill effluents -- EDA of Ah-receptor mediated toxicants, mutagens and endocrine disruptors in sediments and biota -- Ecological relevance of key toxicants in aquatic systems.
520 _aToday more than 5 million chemicals are known and roughly 100,000 of them are frequently used, with both numbers rising. Many of these chemicals are ultimately released into the environment and may cause adverse effects to ecosystems and human health. Effect-directed analysis (EDA) is a promising tool for identifying predominant toxicants in complex, mostly environmental mixtures combining effect testing, fractionation and chemical analysis. In the present book leading experts in the field provide an overview of relevant approaches and tools used in EDA. This includes diagnostic biological tools, separation techniques and advanced analytical and computer tools for toxicant identification and structure elucidation. Examples of the successful application of EDA are discussed such as the identification of mutagens in airborne particles and sediments, of endocrine disruptors in aquatic ecosystems and of major toxicants in pulp and paper mill effluents. This book is a valuable, comprehensive and interdisciplinary source of information for environmental scientists and environmental agencies dealing with the analysis, monitoring and assessment of environmental contamination.
650 0 _aEnvironmental sciences.
650 0 _aAnalytical biochemistry.
650 0 _aGeochemistry.
650 0 _aEnvironmental chemistry.
650 0 _aEnvironmental toxicology.
650 0 _aPollution.
650 1 4 _aEnvironment.
650 2 4 _aEnvironmental Chemistry.
650 2 4 _aGeochemistry.
650 2 4 _aAnalytical Chemistry.
650 2 4 _aEnvironmental Monitoring/Analysis.
650 2 4 _aEcotoxicology.
650 2 4 _aPollution, general.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642183836
830 0 _aThe Handbook of Environmental Chemistry,
_x1867-979X ;
_v15
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-3-642-18384-3
596 _a19
942 _cLIBRO_ELEC
999 _c203605
_d203605