000			03170nam a22004455i 4500
001			u376952
003			SIRSI
005			20160812084438.0
007			cr nn 008mamaa
008			110121s2010 au | s |||| 0|eng d
020			_a9783709100455 _9978-3-7091-0045-5
040			_cMX-MeUAM
050		4	_aQH324.2-324.25
082	0	4	_a570.285 _223
100	1		_aFrishman, Dmitrij. _eauthor.
245	1	0	_aStructural Bioinformatics of Membrane Proteins _h[recurso electrónico] / _cby Dmitrij Frishman.
264		1	_aVienna : _bSpringer Vienna, _c2010.
300			_aXI, 281 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aEvolutionary origins of membrane proteins -- Molecular archeological studies of transmembrane transport systems -- Resource for structure related information on transmembrane proteins -- Topology prediction of membrane proteins: how distantly related homologs come into play -- Transmembrane beta-barrel protein structure prediction -- Multiple alignment of transmembrane protein sequences -- Prediction of re-entrant regions and other structural features beyond traditional topology models -- Dual-topology: one sequence, two topologies -- Predicting the burial/exposure status of transmembrane residues in helical membrane proteins -- Helix-helix interaction patterns in membrane proteins -- Predicting residue and helix contacts in membrane proteins -- Natural constraints, folding, motion, and structural stability in transmembrane helical proteins -- Prediction of three-dimensional transmembrane helical protein structures -- GPCRs: Past, present, and future.
520			_aThis book is the first one specifically dedicated to the structural bioinformatics of membrane proteins. With a focus on membrane proteins from the perspective of bioinformatics, the present work covers a broad spectrum of topics in evolution, structure, function, and bioinformatics of membrane proteins focusing on the most recent experimental results. Leaders in the field who have recently reported breakthrough advances cover algorithms, databases and their applications to the subject. The increasing number of recently solved membrane protein structures makes the expert coverage presented here very timely. Structural bioinformatics of membrane proteins has been an active area of research over the last thee decades and proves to be a growing field of interest.
650		0	_aComputer science.
650		0	_aChemistry.
650		0	_aBioinformatics.
650		0	_aBiological models.
650	1	4	_aComputer Science.
650	2	4	_aComputational Biology/Bioinformatics.
650	2	4	_aSystems Biology.
650	2	4	_aTheoretical and Computational Chemistry.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783709100448
856	4	0	_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-3-7091-0045-5
596			_a19
942			_cLIBRO_ELEC
999			_c204832 _d204832