000 03257nam a22005055i 4500
001 u377205
003 SIRSI
005 20160812084451.0
007 cr nn 008mamaa
008 101211s2011 ja | s |||| 0|eng d
020 _a9784431538806
_9978-4-431-53880-6
040 _cMX-MeUAM
050 4 _aR856-857
082 0 4 _a610.28
_223
100 1 _aNomura, Taishin.
_eeditor.
245 1 0 _aHarnessing Biological Complexity
_h[recurso electrónico] :
_bAn Introduction to Computational Physiology /
_cedited by Taishin Nomura, Yoshiyuki Asai.
264 1 _aTokyo :
_bSpringer Japan :
_bImprint: Springer,
_c2011.
300 _aX, 190p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aA First Course in “In Silico Medicine” ;
_v1
505 0 _aI. Introduction -- II. Modeling Cellular Dynamics -- III. Dynamics of Cellular Networks -- IV. Application of ISIDE to Create Models -- V. Key Consepts of insilicoML.
520 _aThe challenge for the biosciences in the twenty-first century is to integrate genome sequencing information into a better understanding of biology, physiology, and human pathology. Such attempts at integration are moving the world toward a new generation of bioscience and bioengineering, where biological, physiological, and pathological information from humans and other living animals can be quantitatively described in silico across multiple scales of time and size and through diverse hierarchies of organization — from molecules to cells and organs, to individuals. To "harness" such complexity, international communities of integrative bioscientists and bioengineers aim to establish frameworks and information infrastructures for describing biological structures and physiological functions on multiple scales of time and space. This textbook includes a public platform to describe physiological functions using mathematical equations and guides the reader to perform mathematical modeling and computer simulations, to combine existing models as well as to create new models. Accessible to biologists, physiologists, and students of the sciences, with illustrative details provided when necessary, this book seeks to achieve a systematic way of harnessing biological complexity. Sharing the databases among communities worldwide will help to find comprehensive answers to all the important questions.
650 0 _aEngineering.
650 0 _aMedicine.
650 0 _aBiochemistry.
650 0 _aPhysics.
650 0 _aBiomedical engineering.
650 1 4 _aEngineering.
650 2 4 _aBiomedical Engineering.
650 2 4 _aComplexity.
650 2 4 _aMolecular Medicine.
650 2 4 _aMedicinal Chemistry.
700 1 _aAsai, Yoshiyuki.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9784431538790
830 0 _aA First Course in “In Silico Medicine” ;
_v1
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-4-431-53880-6
596 _a19
942 _cLIBRO_ELEC
999 _c205085
_d205085