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008 101031s2010 it | s |||| 0|eng d
020 _a9788847016439
_9978-88-470-1643-9
040 _cMX-MeUAM
050 4 _aRB155.8
082 0 4 _a615.895
_223
100 1 _aGiacca, Mauro.
_eauthor.
245 1 0 _aGene Therapy
_h[recurso electrónico] /
_cby Mauro Giacca.
264 1 _aMilano :
_bSpringer Milan,
_c2010.
300 _aXXI, 303 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _ato Gene Therapy -- Therapeutic Nucleic Acids -- Methods for Gene Delivery -- Clinical Applications of Gene Therapy -- Ethical and Social Problems of Gene Therapy.
520 _aThis book presents to the reader a comprehensive and detailed, yet easily accessible, description of the whole field of gene therapy. It covers topics ranging from vector development to the results of the most recent clinical trials. It includes descriptions of lentiviral and AAV vector development, of therapeutic gene selection (including siRNAs, shRNAs, and microRNAs), and of the most recent clinical applications of gene therapy for diseases of the eye, the cardiovascular system, and the central nervous system. Of note, the book only considers conditions for which transfer of genetic material has already progressed to clinical applications or is close to doing so. The language is plain and, whenever possible, non-technical. Since the book is intended to be a textbook in the field of gene therapy in both the basic science and clinical fields, whenever technical descriptions are required these are provided. Readers will include graduate students in the life sciences area in their final years of study, PhD students, and medical doctors specializing in different fields of internal and specialist medicine, in addition to research scientists working in various areas of current biomedical research.
650 0 _aMedicine.
650 0 _aGene therapy.
650 0 _aMedical virology.
650 0 _aGenetic engineering.
650 0 _aInternal medicine.
650 1 4 _aBiomedicine.
650 2 4 _aGene Therapy.
650 2 4 _aMolecular Medicine.
650 2 4 _aInternal Medicine.
650 2 4 _aGenetic Engineering.
650 2 4 _aVirology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9788847016422
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-88-470-1643-9
596 _a19
942 _cLIBRO_ELEC
999 _c205201
_d205201