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001			u377598
003			SIRSI
005			20160812084510.0
007			cr nn 008mamaa
008			100301s2010 ne | s |||| 0|eng d
020			_a9789048133758 _9978-90-481-3375-8
040			_cMX-MeUAM
050		4	_aQH588.S83
082	0	4	_a571.6 _223
100	1		_aUlrich, Henning. _eeditor.
245	1	0	_aPerspectives of Stem Cells _h[recurso electrónico] : _bFrom tools for studying mechanisms of neuronal differentiation towards therapy / _cedited by Henning Ulrich.
264		1	_aDordrecht : _bSpringer Netherlands, _c2010.
300			_aXV, 290 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aNeural Induction -- Neurogenesis: A Change of Paradigms -- Neurogenesis in the Olfactory Epithelium -- Cell Diversification During Neural Crest Ontogeny: The Neural Crest Stem Cells -- Intermediate Filament Expression in Mouse Embryonic Stem Cells and Early Embryos -- Aneuploidy in Embryonic Stem Cells -- Retrotransposition and Neuronal Diversity -- Directing Differentiation of Embryonic Stem Cells into Distinct Neuronal Subtypes -- Neurotransmitters as Main Players in the Neural Differentiation and Fate Determination Game -- Rhythmic Expression of Notch Signaling in Neural Progenitor Cells -- Neuron-Astroglial Interactions in Cell Fate Commitment in the Central Nervous System -- The Origin of Microglia and the Development of the Brain -- Tissue Biology of Proliferation and Cell Death Among Retinal Progenitor Cells -- Potential Application of Very Small Embryonic Like (VSEL) Stem Cells in Neural Regeneration -- Embryonic Stem Cell Transplantation for the Treatment of Parkinson's Disease -- Functional Multipotency of Neural Stem Cells and Its Therapeutic Implications -- Dual Roles of Mesenchymal Stem Cells in Spinal Cord Injury: Cell Replacement Therapy and as a Model System to Understand Axonal Repair.
520			_aStem cells are fascinating cell types. They can replicate themselves forever while retaining the potential to generate progeny with speci?c functions. Because of these special properties, stem cells have been subjects of intensive investigation, from understanding basic mechanisms underlying tissue generation, to modeling human diseases, to application for cell replacement therapy. Stem cells come in different forms. For example, mouse embryonic stem cells can general all cell types in a body, either in a dish or when put back into mouse embryos. On the other hand, neural stem cells in the adult brain generate neurons and glia cells that contribute to the brain’s plasticity. Rapid progress has been made in the stem cell ?eld with discov- ies published in a record speed. A quick Pubmed search has returned 2789 hits for “embryonic stem cells” and 815 hits for “adult neural stem cells/neurogenesis” in the year 2008 alone. It remains a taunting task for all who are interested in stem cells to keep up with rapidly accumulating literatures. The “Perspectives of Stem Cells” by a truly international team of experts provides a timely and invaluable highlight of the stem cell ?eld gearing toward future therapeutic applications in the nervous system. Stem cells with neural potentials have attracted a lot of attention because of their promise for cell replacement therapy, ranging from degenerative neurological dis- ders to spinal cord injuries.
650		0	_aLife sciences.
650		0	_aMedicine.
650		0	_aNeurosciences.
650		0	_aNeurochemistry.
650		0	_aStem cells.
650		0	_aDevelopmental biology.
650	1	4	_aLife Sciences.
650	2	4	_aStem Cells.
650	2	4	_aNeurosciences.
650	2	4	_aDevelopmental Biology.
650	2	4	_aNeurochemistry.
650	2	4	_aBiomedicine general.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9789048133741
856	4	0	_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-90-481-3375-8
596			_a19
942			_cLIBRO_ELEC
999			_c205478 _d205478