000			04058cam a2200481Ii 4500
001			u380157
003			SIRSI
005			20160812084633.0
006			m o d
007			cr cnu---unuuu
008			131114s2014 enka obf 001 0 eng d
040			_aOPELS _beng _erda _epn _cOPELS _dCUX _dGGVRL _dOCLCQ _dYDXCP _dNLGGC
020			_z9780124078673
020			_z0124078672
029	1		_aDEBSZ _b405351895
029	1		_aNZ1 _b15341990
029	1		_aNLGGC _b389717991
050		4	_aQP99.3.L52
082	0	4	_a612.12 _223
049			_aTEFA
245	0	4	_aThe HDL handbook _h[recurso electrónico] : _bbiological functions and clinical implications / _cedited by Tsugikazu Komoda.
250			_aSecond edition.
264		1	_aLondon : _bAcademic Press, _c[2014]
300			_a1 online resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
588	0		_aPrint version record.
500			_aPrevious edition: London: Elsevier, 2010.
504			_aIncludes bibliographical references and index.
520			_aThe HDL Handbook: Biological Functions to Clinical Implications brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases. In addition, researchers and clinicians working with an aging population, corporate researchers, post-doctorates; medical students and graduate students will find this publication useful because the scope of coverage includes basic science, genetics, epidemiology, and treatment of HDL cholesterol as well as potential targets to modify HDL cholesterol. Provides bench-to-bedside coverage of HDL with thorough coverage of basic science, genetics, epidemiology, and treatment Presents a complete update with six new chapters on the latest advances in HDL cholesterol research with international perspective New chapters on proteomics, clinical impact of LCAT in HDL metabolism, and an in-depth discussion of potential targets to modify HDL provide a translational reference for clinicians.
505	0		_a1. Introduction of HDL molecules, past and brief future / Mari Tabuchi, Tsugikazu Komoda -- 2. Apolipoprotein A-I mutations and clinical evaluation / Akira Matsunaga -- 3. The complexity of high-density lipoproteins / Bela F. Asztalos, Mariko Tani, Brian Ishida -- 4. Reverse cholesterol transport in HDL metabolism : modulation of structural and functional features of HDL particles / Elise F. Villard, Maryse Guerin -- 5. Role of ATP-binding cassette transporters A1 and G1 in reverse cholesterol transport and atherosclerosis / Makoto Ayaori, Katsunori Ikewaki -- 6. Sphingolipids and HDL metabolism / Xian-Cheng Jiang, Zhiqiang Li, Amirfarbod Yazdanyar -- 7. Role of lecithin : cholesterol acyltransferase in HDL metabolism and atherosclerosis / Lusana Ahsan [and six others] -- 8. Cholesteryl ester transfer protein inhibitors : a hope remains / Akihiro Inazu -- 9. HDL apoprotein mimetic peptides as anti-inflammatory molecules / Godfrey S. Getz, Catherine A. Reardon -- 10. Oxidized high-density lipoprotein : friend or foe / Toshiyuki Matsunaga, Akira Hara, Tsugikazu Komoda -- 11. Current aspects of paraoxonase-1 research / Mike Mackness, Bharti Mackness -- 12. Proteomic diversity in HDL : a driving force for particle function and target for therapeutic intervention / Scott M. Gordon.
650		0	_aHigh density lipoproteins _xPhysiological effect.
650		0	_aHigh density lipoproteins _xMetabolism.
650		2	_aCholesterol, HDL _vHandbooks.
655		4	_aElectronic books.
700	1		_aKomoda, Tsugikazu, _eeditor.
776	0	8	_iPrint version: _tHDL handbook. _bSecond edition _z9780124078673 _w(OCoLC)861317544
856	4	0	_zLibro electrónico _3ScienceDirect _uhttp://148.231.10.114:2048/login?url=http://www.sciencedirect.com/science/book/9780124078673
596			_a19
942			_cLIBRO_ELEC
999			_c207078 _d207078