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040 _aOPELS
_cOPELS
_dOCLCQ
_dCUX
_dYDXCP
_dOCLCF
020 _a9780123878304 (e-ISBN)
020 _a0123878306 (e-ISBN)
020 _a9781283626149 (e-ISBN)
020 _a1283626144 (e-ISBN)
020 _z9780123878298 (p-ISBN)
020 _z0123878292 (p-ISBN)
029 1 _aAU@
_b000050174885
029 1 _aAU@
_b000051222240
029 1 _aNZ1
_b15188293
029 1 _aDEBSZ
_b405345003
050 4 _aRC930.4
_b.G46 2013
082 0 4 _a616.7/1
_223
049 _aTEFA
245 0 0 _aGenetics of bone biology and skeletal disease
_h[recurso electrónico] /
_cedited by Rajesh V. Thakker ... [et al.].
260 _aLondon :
_bAcademic Press,
_c2013.
300 _a1 online resource (xi, 621 p.) :
_bill.
588 _aDescription based on online resource (viewed January 31, 2013).
520 _aThis book identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluations of treatments. The book is aimed at all students of bone biology and genetics, and with this in mind, it includes general introductory chapters on genetics and bone biology and more specific disease-orientated chapters, which comprehensively summarize the clinical, genetic, molecular genetic, animal model, functional and molecular pathology, diagnostic, counselling and treatment aspects of each disorder. Saves academic, medical, and pharma researchers time in quickly accessing the very latest details on a broad range of genetic bone issues, as opposed to searching through thousands of journal articles. Provides a common language for bone biologists and geneticists to discuss the development of bone cells and genetics and their interactions in the development of disease Researchers in all areas bone biology and genetics will gain insight into how clinical observations and practices can feed back into the research cycle and will, therefore, be able to develop more targeted genomic and proteomic assays For those clinical researchers who are also MDs, correct diagnosis (and therefore correct treatment) of bone diseases depends on a strong understanding of the molecular basis for the disease.
504 _aIncludes bibliographical references and index.
650 0 _aBones
_xDiseases
_xGenetic aspects.
650 1 2 _aBone Diseases
_xgenetics.
650 7 _aBones
_xDiseases
_xGenetic aspects.
_2fast
_0(OCoLC)fst00836010
655 4 _aElectronic books.
700 1 _aThakker, R. V.
776 0 8 _iPrint version:
_tGenetics of bone biology and skeletal disease.
_dLondon ; Waltham, MA : Academic Press, c 2013
_z9780123878298
_w(OCoLC)714729532
856 4 0 _zLibro electrónico
_3ScienceDirect
_uhttp://148.231.10.114:2048/login?url=http://www.sciencedirect.com/science/book/9780123878298
596 _a19
942 _cLIBRO_ELEC
999 _c207426
_d207426