000			01846nam a22002417a 4500
003			MX-MeUAM
005			20171115120643.0
008			171114s2016 ne a frb 001 0 eng d
020			_a9780128033098
040			_dMX-MeUAM
050			_aQH447 _bG46 2016
245	0	0	_aGenome stability : _bfrom virus to human application / _cedited by Igor Kovalchuk, Olga Kovalchuk.
260			_aAmsterdam : _bElsevier/Academic Press, _c2016.
300			_axxii, 690 p. : _bil. a col. ; _c29 cm.
490	0		_aTranslational epigenetics
504			_aIncluye referencias bibliográficas e índice.
520			_aGenome Stability: From Virus to Human Application covers the genome stability of DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes, and mammals, with the latter including major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability, as well as changes in genome stability in response to aging. Every species has to preserve the integrity of its genome to ensure faithful passage of genetic information to the progeny. At the same time, there are times during the life of the organism and population in general when a fine balance in genome stability and diversification has to be made to benefit the survival of the species. This book teaches the reader how various species maintain this fine balance in genome stability and genome diversification in response to their environments. The book also covers how epigenetic factors contribute to genome stability and how species pass the memory of the encounters to the progeny, thus influencing the genome of the progeny in an indirect manner.
650		0	_aGenomes.
650		7	_aGenomas.
700	1		_aKovalchuk, Olga _c(Physician), _eed.
700	1		_aKovalchuk, Igor, _eed.
942			_cLIBRO
999			_c223585 _d223585