000 03153nam a22004575i 4500
001 978-3-319-48066-4
003 DE-He213
005 20180206182932.0
007 cr nn 008mamaa
008 161221s2016 gw | s |||| 0|eng d
020 _a9783319480664
_9978-3-319-48066-4
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
100 1 _aRotte, Anand.
_eauthor.
245 1 0 _aImmunotherapy of Melanoma
_h[recurso electrónico] /
_cby Anand Rotte, Madhuri Bhandaru.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2016.
300 _aXI, 434 p. 59 illus., 52 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aPreface -- Melanoma -- Tumor immunology -- Immune based drugs approved for treatment of melanoma -- Promising immunotherapeutic approaches in clinical trials -- Challenges of immunotherapy -- Index.
520 _aThis book focusses on the different types of immunotherapeutics that are currently being used and developed for the treatment of melanoma. In recent years, immunotherapy has revolutionized the treatment of metastatic melanoma and other types of cancer. Discussing treatment options for melanoma and the success of immunotherapy along with the challenges of immunotherapy, this book covers epidemiology, susceptibility genes, and treatment recommendations from Society for Immunotherapy of Cancer, as well as immune based therapies such as aldesleukin, Intron-A, Sylatron, Yervoy, Opdivo, Keytruda, Imlygic, DC vaccines and adoptive cell therapy. The detailed information included on the key immune cells involved in anti-tumor immune response and immune-inhibitory mechanisms in tumor microenvironment will aid the understanding of tumor immunology. Both academic as well as industry-based researchers, developing novel anti-cancer therapies, will also benefit from the details of promising molecular targets and immunotherapeutic strategies under investigation. With 132 illustrations including synopsis tables for important information, over 1200 references (majority of which are openly accessible) and details of more than 150 ongoing clinical trials, this book is a valuable source of information for health care providers as well as cancer biologists interested in learning about melanoma and the significant advances made by immunotherapy.
650 0 _aMedicine.
650 0 _aCancer research.
650 0 _aOncology.
650 1 4 _aBiomedicine.
650 2 4 _aCancer Research.
650 2 4 _aOncology.
700 1 _aBhandaru, Madhuri.
_eauthor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319480657
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-48066-4
912 _aZDB-2-SBL
942 _cLIBRO_ELEC
999 _c225445
_d225445