| 000 | 02455nam a22004455i 4500 | ||
|---|---|---|---|
| 001 | 978-3-319-46091-8 | ||
| 003 | DE-He213 | ||
| 005 | 20180206182936.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 161107s2016 gw | s |||| 0|eng d | ||
| 020 |
_a9783319460918 _9978-3-319-46091-8 |
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| 050 | 4 | _aRC261-271 | |
| 072 | 7 |
_aMJCL _2bicssc |
|
| 072 | 7 |
_aMED062000 _2bisacsh |
|
| 082 | 0 | 4 |
_a614.5999 _223 |
| 245 | 1 | 0 |
_aResistance to Tyrosine Kinase Inhibitors _h[recurso electrónico] / _cedited by Daniele Focosi. |
| 264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2016. |
|
| 300 |
_aXIII, 188 p. 8 illus., 6 illus. in color. _bonline resource. |
||
| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
||
| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF _2rda |
||
| 490 | 1 |
_aResistance to Targeted Anti-Cancer Therapeutics, _x2196-5501 |
|
| 505 | 0 | _aTyrosine Kinase Signaling Pathways in Normal and Cancer Cells -- Resistance to Tyrosine Kinase Inhibitors in different types of solid cancer -- The Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia: An Overview -- Resistance to FLT3 Inhibitors -- Resistance to ALK inhibitors -- Resistance to Angiokinase Inhibitors -- Indications for Tyrosine Kinase Inhibitors in the Treatment of Solid Tumors. | |
| 520 | _aThe volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most commonly used classes of tyrosine kinase inhibitors, and will focus specific chapters on resistance to BCR-ABL1, FLT3, angiokinase family members, and ALK inhibitors. | ||
| 650 | 0 | _aMedicine. | |
| 650 | 0 | _aCancer research. | |
| 650 | 1 | 4 | _aBiomedicine. |
| 650 | 2 | 4 | _aCancer Research. |
| 700 | 1 |
_aFocosi, Daniele. _eeditor. |
|
| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer eBooks | |
| 776 | 0 | 8 |
_iPrinted edition: _z9783319460901 |
| 830 | 0 |
_aResistance to Targeted Anti-Cancer Therapeutics, _x2196-5501 |
|
| 856 | 4 | 0 |
_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-46091-8 |
| 912 | _aZDB-2-SBL | ||
| 942 | _cLIBRO_ELEC | ||
| 999 |
_c225511 _d225511 |
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