000			03719nam a22005295i 4500
001			978-3-319-28755-3
003			DE-He213
005			20180206182948.0
007			cr nn 008mamaa
008			160427s2016 gw | s |||| 0|eng d
020			_a9783319287553 _9978-3-319-28755-3
050		4	_aQH359-425
072		7	_aPSAJ _2bicssc
072		7	_aSCI027000 _2bisacsh
082	0	4	_a576.8 _223
100	1		_aForsdyke, Donald R. _eauthor.
245	1	0	_aEvolutionary Bioinformatics _h[recurso electrónico] / _cby Donald R. Forsdyke.
250			_a3rd ed. 2016.
264		1	_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2016.
300			_aXXXIV, 471 p. 116 illus., 24 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aPart 1. Information and DNA -- 1. Memory ? A Phenomenon of Arrangement -- 2. Chargaff?s First Parity Rule -- 3. Information Levels and Barriers -- Part 2. Parity and Non-Parity -- 4. Chargaff?s Second Parity Rule -- 5. Stems and Loops -- 6. Chargaff?s Cluster Rule -- Part 3. Variation and Speciation -- 7. Mutation -- 8. Species Survival and Arrival -- 9. The Weak Point -- 10. Chargaff?s GC Rule -- 11. Homostability -- Part 4. Conflict within Genomes -- 12. Conflict Resolution -- 13. Exons and Introns -- 14. Complexity -- Part 5. Conflict between Genomes -- 15. Self/Not-Self? -- 16. The Crowded Cytosol -- Part 6. Sex and Error-Correction -- 17. Rebooting the Genome -- 18. The Fifth Letter -- Part 7. Information and Mind -- 19. Memory ? What is Arranged and Where? -- 20.Certainty Now Uncertain.
520			_aNow in its third edition and supplemented with more online material, this book aims to make the "new" information-based (rather than gene-based) bioinformatics intelligible both to the "bio" people and the "info" people. Books on bioinformatics have traditionally served gene-hunters, and biologists who wish to construct family trees showing tidy lines of descent. While dealing extensively with the exciting topics of gene discovery and database-searching, such books have hardly considered genomes as information channels through which multiple forms and levels of information have passed through the generations. This ?new bioinformatics? contrasts with the "old" gene-based bioinformatics that so preoccupies previous texts. Forms of information that we are familiar with (mental, textual) are related to forms with which we are less familiar (hereditary). The book extends a line of evolutionary thought that leads from the nineteenth century (Darwin, Butler, Romanes, Bateson), through the twentieth (Goldschmidt, White), and into the twenty first (the final works of the late Stephen Jay Gould). Long an area of controversy, diverging views may now be reconciled.
650		0	_aLife sciences.
650		0	_aHuman genetics.
650		0	_aProteomics.
650		0	_aSystems biology.
650		0	_aEvolutionary biology.
650		0	_aStatistics.
650	1	4	_aLife Sciences.
650	2	4	_aEvolutionary Biology.
650	2	4	_aSystems Biology.
650	2	4	_aProteomics.
650	2	4	_aStatistics for Life Sciences, Medicine, Health Sciences.
650	2	4	_aHuman Genetics.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783319287539
856	4	0	_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-28755-3
912			_aZDB-2-SBL
942			_cLIBRO_ELEC
999			_c225753 _d225753