000 03295nam a22004455i 4500
001 978-3-319-40764-7
003 DE-He213
005 20180206183016.0
007 cr nn 008mamaa
008 161006s2016 gw | s |||| 0|eng d
020 _a9783319407647
_9978-3-319-40764-7
050 4 _aRC321-580
072 7 _aPSAN
_2bicssc
072 7 _aMED057000
_2bisacsh
082 0 4 _a612.8
_223
245 1 0 _aGlial Cells in Health and Disease of the CNS
_h[recurso electrónico] /
_cedited by Rommy von Bernhardi.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2016.
300 _aXI, 348 p. 46 illus., 35 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v949
505 0 _aGlial cells and the Integrity of the CNS -- NG2-glia: More than Progenitor Cells -- Pharmacological tools to study the role of astrocytes in neural network function -- "Microglia function in the normal brain? -- Physiological functions of glial cell hemichannels -- Role of astrocytes in central respiratory chemoreception -- Purine signaling and microglial wrapping -- Oligodendrocytes, functioning in a delicate balance between high metabolic requirements and oxidative damage -- Schwann cell and axon: an interlaced unit, from action potential to phenotype expression -- Age-dependent changes in the activation and regulation of microglia -- Astrocyte dysfunction in developmental neurometabolic diseases -- Microglia in cancer: for good or for bad? -- Peripheral inflammation and demyelinating diseases -- Regulation of oligodendrocyte differentiation and myelination by nuclear receptors: role in neurodegenerative disorders -- The Role of Galectin-3: from Oligodendroglial Differentiation and Myelination to Demyelination and Remyelination Processes in a Cuprizone-Induced Demyelination Model -- Prenatal systemic hypoxia-ischemia and oligodendroglia loss in cerebellum .
520 _aA timely overview covering the three major types of glial cells in the central nervous system - astrocytes, microglia, and oligodendrocytes. New findings on glia biology are overturning a century of conventional thinking about how the brain operates and are expanding our knowledge about information processing in the brain. The book will present recent research findings on the role of glial cells in both healthy function and disease. It will comprehensively cover a broad spectrum of topics while remaining compact in size.
650 0 _aMedicine.
650 0 _aNeurosciences.
650 1 4 _aBiomedicine.
650 2 4 _aNeurosciences.
700 1 _avon Bernhardi, Rommy.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319407623
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v949
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-40764-7
912 _aZDB-2-SBL
942 _cLIBRO_ELEC
999 _c226292
_d226292