000 | 04240nam a22005415i 4500 | ||
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001 | 978-3-319-31973-5 | ||
003 | DE-He213 | ||
005 | 20180206183020.0 | ||
007 | cr nn 008mamaa | ||
008 | 160614s2016 gw | s |||| 0|eng d | ||
020 |
_a9783319319735 _9978-3-319-31973-5 |
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050 | 4 | _aQH491 | |
072 | 7 |
_aPSC _2bicssc |
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072 | 7 |
_aSCI072000 _2bisacsh |
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082 | 0 | 4 |
_a571.8 _223 |
245 | 1 | 0 |
_aMolecular Mechanisms of Cell Differentiation in Gonad Development _h[recurso electrónico] / _cedited by Rafal P. Piprek. |
264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2016. |
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300 |
_aXII, 434 p. 52 illus., 48 illus. in color. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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490 | 1 |
_aResults and Problems in Cell Differentiation, _x0080-1844 ; _v58 |
|
505 | 0 | _aEarly Development of the Gonads ? Origin and Differentiation of the Somatic Cells of the Genital Ridges -- The formation and migration of primordial germ cells in mouse and man -- The Gonadal Supporting Cell Lineage and Mammalian Sex Determination: the Differentiation of Sertoli and Granulosa Cells -- Mesonephric cell migration into the gonads and vascularization are processes crucial for testis development -- Origin and Differentiation of Androgen-producing Cells in the Gonads -- Germ cell commitment to oogenic versus spermatogenic pathway - the role of retinoic acid -- Ovarian Folliculogenesis -- Control of oocyte growth and development by intercellular communication within the follicular niche -- Biology of the Sertoli cell in the Fetal, Pubertal and Adult Mammalian Testis -- Mechanisms Regulating Spermatogonial Differentiation -- Stem cells in mammalian gonads -- A Role of microRNAs in Cell Differentiation during Gonad Development -- The Battle of the Sexes: Human Sex Development and its Disorders -- Methods for the study of gonadal development. | |
520 | _aThis book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions. The individual chapters review the origin and differentiation of the somatic cells of the genital ridges; the formation and migration of primordial germ cells in mouse and man; the gonadal supporting cell lineage and mammalian sex determination; differentiation of Sertoli and granulosa cells; mesonephric cell migration into the gonads and vascularization; origin and differentiation of androgen-producing cells in the gonads; germ cell commitment to the oogenic versus spermatogenic pathway and the role of retinoic acid; ovarian folliculogenesis; control of oocyte growth and development by intercellular communication within the follicular niche; biology of the Sertoli cell in the fetal, pubertal and adult mammalian testis; mechanisms regulating spermatogonial differentiation; stem cells in mammalian gonads; the role of microRNAs in cell differentiation during gonad development; human sex development and its disorders; as well as methods for the study of gonadal development. | ||
650 | 0 | _aLife sciences. | |
650 | 0 | _aCytogenetics. | |
650 | 0 | _aMolecular biology. | |
650 | 0 | _aReproductive medicine. | |
650 | 0 | _aStem cells. | |
650 | 0 | _aDevelopmental biology. | |
650 | 1 | 4 | _aLife Sciences. |
650 | 2 | 4 | _aDevelopmental Biology. |
650 | 2 | 4 | _aStem Cells. |
650 | 2 | 4 | _aCytogenetics. |
650 | 2 | 4 | _aMolecular Medicine. |
650 | 2 | 4 | _aReproductive Medicine. |
700 | 1 |
_aPiprek, Rafal P. _eeditor. |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9783319319711 |
830 | 0 |
_aResults and Problems in Cell Differentiation, _x0080-1844 ; _v58 |
|
856 | 4 | 0 |
_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-31973-5 |
912 | _aZDB-2-SBL | ||
942 | _cLIBRO_ELEC | ||
999 |
_c226392 _d226392 |