000 04240nam a22005415i 4500
001 978-3-319-31973-5
003 DE-He213
005 20180206183020.0
007 cr nn 008mamaa
008 160614s2016 gw | s |||| 0|eng d
020 _a9783319319735
_9978-3-319-31973-5
050 4 _aQH491
072 7 _aPSC
_2bicssc
072 7 _aSCI072000
_2bisacsh
082 0 4 _a571.8
_223
245 1 0 _aMolecular Mechanisms of Cell Differentiation in Gonad Development
_h[recurso electrónico] /
_cedited by Rafal P. Piprek.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2016.
300 _aXII, 434 p. 52 illus., 48 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aResults and Problems in Cell Differentiation,
_x0080-1844 ;
_v58
505 0 _aEarly Development of the Gonads ? Origin and Differentiation of the Somatic Cells of the Genital Ridges -- The formation and migration of primordial germ cells in mouse and man -- The Gonadal Supporting Cell Lineage and Mammalian Sex Determination: the Differentiation of Sertoli and Granulosa Cells -- Mesonephric cell migration into the gonads and vascularization are processes crucial for testis development -- Origin and Differentiation of Androgen-producing Cells in the Gonads -- Germ cell commitment to oogenic versus spermatogenic pathway - the role of retinoic acid -- Ovarian Folliculogenesis -- Control of oocyte growth and development by intercellular communication within the follicular niche -- Biology of the Sertoli cell in the Fetal, Pubertal and Adult Mammalian Testis -- Mechanisms Regulating Spermatogonial Differentiation -- Stem cells in mammalian gonads -- A Role of microRNAs in Cell Differentiation during Gonad Development -- The Battle of the Sexes: Human Sex Development and its Disorders -- Methods for the study of gonadal development.
520 _aThis book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions. The individual chapters review the origin and differentiation of the somatic cells of the genital ridges; the formation and migration of primordial germ cells in mouse and man; the gonadal supporting cell lineage and mammalian sex determination; differentiation of Sertoli and granulosa cells; mesonephric cell migration into the gonads and vascularization; origin and differentiation of androgen-producing cells in the gonads; germ cell commitment to the oogenic versus spermatogenic pathway and the role of retinoic acid; ovarian folliculogenesis; control of oocyte growth and development by intercellular communication within the follicular niche; biology of the Sertoli cell in the fetal, pubertal and adult mammalian testis; mechanisms regulating spermatogonial differentiation; stem cells in mammalian gonads; the role of microRNAs in cell differentiation during gonad development; human sex development and its disorders; as well as methods for the study of gonadal development.
650 0 _aLife sciences.
650 0 _aCytogenetics.
650 0 _aMolecular biology.
650 0 _aReproductive medicine.
650 0 _aStem cells.
650 0 _aDevelopmental biology.
650 1 4 _aLife Sciences.
650 2 4 _aDevelopmental Biology.
650 2 4 _aStem Cells.
650 2 4 _aCytogenetics.
650 2 4 _aMolecular Medicine.
650 2 4 _aReproductive Medicine.
700 1 _aPiprek, Rafal P.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319319711
830 0 _aResults and Problems in Cell Differentiation,
_x0080-1844 ;
_v58
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-31973-5
912 _aZDB-2-SBL
942 _cLIBRO_ELEC
999 _c226392
_d226392