000 04266nam a22004695i 4500
001 978-3-319-11578-8
003 DE-He213
005 20180206183023.0
007 cr nn 008mamaa
008 151126s2016 gw | s |||| 0|eng d
020 _a9783319115788
_9978-3-319-11578-8
050 4 _aRC321-580
072 7 _aPSAN
_2bicssc
072 7 _aMED057000
_2bisacsh
082 0 4 _a612.8
_223
245 1 0 _aRodent Model as Tools in Ethical Biomedical Research
_h[recurso electrónico] /
_cedited by Monica Levy Andersen, Sergio Tufik.
250 _a1st ed. 2016.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2016.
300 _aXVII, 516 p. 194 illus., 137 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aPART 1 Ethics -- CHAPTER 1 Introduction -- CHAPTER 2 The aspects of the use of rodents in experimental research -- CHAPTER 3 The impact of the environment on laboratory animals -- CHAPTER 4 Basic concepts in alternative methods to the use of animals -- CHAPTER 5 Care and Maintenance of Laboratory Animals -- CHAPTER 6 Euthanasia -- PART 2 Use of Rats -- CHAPTER 7 The Health of Laboratory Animals -- CHAPTER 8 Rats -- CHAPTER 9 The Female Rat -- PART 3 General Procedures and Methods in Rodents Research -- CHAPTER 10 Anaesthesia in Laboratory Animals -- CHAPTER 11 Various Surgical Procedures in Rodents -- CHAPTER 12 Transgenic Animals: Principles, Methods and Applications -- CHAPTER 13 Measuring Electrocardiogram and Heart Rate in Small laboratory animals with Radi-Telemetry -- CHAPTER 14 Gene Expression Studies Using Microarrays -- CHAPTER 15 Brain Microdialysis -- PART 4 Behavioral Models in Rodents -- CHAPTER 16 Sexual Behavior in rats: An Animal Model for the Study of the Neuroendocrine System -- CHAPTER 17 Maternal Behavior -- CHAPTER 18 Behavioral Methods to Study Learning and Memory in Rats -- CHAPTER 19 Animal Tests for Anxiety -- CHAPTER 20 The Plus-Maze Discriminative Avoidance Task: An Ethical Rodent Model for Concomitant Evaluation of Learning, Memory, Anxiety, Motor Activity and their Interactions -- CHAPTER 21 Rodent Models in Psychiatric Research -- PART 5 Other uses of Rodent Models -- CHAPTER 22 Male Reproductive Toxicology -- CHAPTER 23 Sleep Patterns in Rats -- CHAPTER 24 Narcolepsy-Cataplexy in the Rats -- CHAPTER 25 Hypoxia: Introduction of Mechanisms and Consequences -- CHAPTER 26 Assessment of Motor Function in Rodents: Behavioral Models Sharing Simplicity and Multifaceted Applicability Part 1: The Open-Field Test* -- CHAPTER 27 Assessment of Motor Function in Rodents: Behavioral Models Sharing Simplicity and Multifaceted Applicability Part 2: The Catalepsy Test -- CHAPTER 28 Assessment of Motor Function in Rodents: Behavioral Models Sharing Simplicity and Multifaceted Applicability Part 3: Orafacial Dyskinesia -- CHAPTER 29 Experimental Diet Models in the Investigation of Obesity.
520 _aThe objective of this book is to concisely present information with respect to appropriate use of experimental rodents in research. The principles elaborated seek to provide knowledge of the techniques involved in both management and scientific research to all who use laboratory animals, with a focus on the well-being and ethics regarding rodents and also to fortify the awareness of the importance of the animal as a study object and to offer orientation and assistance in conducting laboratory research, education or tests.
650 0 _aMedicine.
650 0 _aNeurosciences.
650 0 _aBehavioral sciences.
650 1 4 _aBiomedicine.
650 2 4 _aNeurosciences.
650 2 4 _aBehavioral Sciences.
700 1 _aAndersen, Monica Levy.
_eeditor.
700 1 _aTufik, Sergio.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319115771
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-11578-8
912 _aZDB-2-SBL
942 _cLIBRO_ELEC
999 _c226460
_d226460