000 03317nam a22004935i 4500
001 978-3-319-46805-1
003 DE-He213
005 20180206183026.0
007 cr nn 008mamaa
008 161219s2016 gw | s |||| 0|eng d
020 _a9783319468051
_9978-3-319-46805-1
050 4 _aR857.T55
072 7 _aPSF
_2bicssc
072 7 _aSCI049000
_2bisacsh
082 0 4 _a612.028
_223
082 0 4 _a571.538
_223
245 1 0 _aMicroarray Bioprinting Technology
_h[recurso electrónico] :
_bFundamentals and Practices /
_cedited by Moo-Yeal Lee.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2016.
300 _aXIII, 175 p. 120 illus., 114 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _a1. Overview of Microarray Bioprinting Technology -- 2. Microarray Spotter and Printing Technologies -- 3. Chip Platforms and Chip Surface Treatments -- 4. Biological Sample Printing -- 5. High Content Cell Staining -- 6. 3D-Cultured Cell Image Acquisition -- 7. High-Content Image Analysis -- 8. Applications of Microarray Bioprinting.
520 _aThis book introduces key fundamentals of microarray bioprinting, including the required chip platforms and associated instruments/devices, experimental protocols for cell printing and biochemical- and cell-based assays, and several example applications. Various bioprinting approaches that allow for the rapid testing of hundreds of different cell culture conditions in combinations on a single chip are discussed in detail. Also covered is high-content, 3D cell-based imaging assays of tissue functions on miniaturized tissue constructs for high-throughput, predictive screening of drug efficacy and toxicity. This is an ideal book for graduate and postgraduate students in the field of biomedical engineering as well as scientists in the pharmaceutical industry. This book also: Broadens readers? understanding of the principles of microarray bioprinting, chip platforms and associated instruments/devices, and surface chemistry for micropatterning of cells on the chip platform Covers the latest developments in printing cells in hydrogels and methods of gelation as well as printing other biological samples in aqueous solutions Illustrates the complete process for cell staining and high-content imaging of 3D cells on the chip and predicting human metabolism and toxicology on the chip.
650 0 _aLife sciences.
650 0 _aBiotechnology.
650 0 _aRegenerative medicine.
650 0 _aTissue engineering.
650 0 _aBiomedical engineering.
650 1 4 _aLife Sciences.
650 2 4 _aRegenerative Medicine/Tissue Engineering.
650 2 4 _aBiomedical Engineering.
650 2 4 _aMicroengineering.
700 1 _aLee, Moo-Yeal.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319468037
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-46805-1
912 _aZDB-2-SBL
942 _cLIBRO_ELEC
999 _c226501
_d226501