000			04296nam a22005055i 4500
001			978-4-431-56050-0
003			DE-He213
005			20180206183103.0
007			cr nn 008mamaa
008			160819s2016 ja | s |||| 0|eng d
020			_a9784431560500 _9978-4-431-56050-0
050		4	_aRC321-580
072		7	_aPSAN _2bicssc
072		7	_aMED057000 _2bisacsh
082	0	4	_a612.8 _223
245	1	0	_aDendrites _h[recurso electrónico] : _bDevelopment and Disease / _cedited by Kazuo Emoto, Rachel Wong, Eric Huang, Casper Hoogenraad.
264		1	_aTokyo : _bSpringer Japan : _bImprint: Springer, _c2016.
300			_aVII, 608 p. 104 illus., 86 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aPart 1 Introduction -- 1 Introduction -- Part 2 Basic biology of dendrites -- 2 Cytoskeletal organization ? actin -- 3 Cytoskeletal organization ? microtubules -- 4 Membrane trafficking mechanisms: -endo/exocytosis -- 5 Synapse to nucleus signaling -- 6 Ultrastructural methods -- 7 Bioimaging of dendritic signaling -- Part 3 Patterning dendritic architecture of neurons and their populations -- 8 Self-avoidance -- 9 Dendritic tiling -- 10 Mosaics and lamination -- 11 Modifying dendritic structure after function -- Part 4 Cellular and molecular control of dendrite development and maintenance -- 12 Molecular control of dendrite development -- 13 Sensory-dependent regulation of dendritic morphology -- 14 Dendrite maintenance -- Part 5 Synapse formation onto dendrites -- 15 Molecular assembly of excitatory synapses -- 16 Localizing receptors and channels across the dendritic arbor -- 17 Synaptic adhesion molecules -- 18 Balancing excitatory and inhibitory inputs -- 19 Assembly and reassembly of synapses -- Part 6 Dendrites in disease -- 20 Dendrite development in autism and autism-related disorders -- 21 Dendrite degeneration in Frontotemporal dementia -- 22 Dendrite degeneration and Glaucoma.
520			_aStudies in human patients and animal models of disease suggest a strong correlation between defects in dendrite development and common neurological disorders such as autism. Much of this book is thus dedicated toward highlighting recent advances in our understanding of the cellular and molecular mechanisms that regulate the development and maintenance of dendrites, a crucial component of neurons. The book begins by presenting the current state of knowledge on the building blocks or cell biology of dendrites. Mechanisms that sculpt the stereotypic architecture of dendritic arbors and shape their connectivity are also discussed, along with recent work describing how dendritic organization and connectivity are perturbed in disease. A unique aspect of the book is its exploration of diverse neuronal cell types across vertebrates and invertebrates, allowing a comparison of mechanisms across distinct circuits and species. The book comprises six parts, which cover the major advances in the field: Part 1, Introduction; Part 2, Basic Biology of Dendrites; Part 3, Patterning Dendritic Architecture of Neurons and Their Populations; Part 4, Cellular and Molecular Control of Dendrite Development and Maintenance; Part 5, Synapse Formation onto Dendrites; and Part 6, Dendrites in Disease. The book offers an excellent point of entry for students interested in neuroscience, as well as for clinicians.
650		0	_aMedicine.
650		0	_aNeurosciences.
650		0	_aNeurology.
650		0	_aAnimal models in research.
650	1	4	_aBiomedicine.
650	2	4	_aNeurosciences.
650	2	4	_aNeurology.
650	2	4	_aAnimal Models.
700	1		_aEmoto, Kazuo. _eeditor.
700	1		_aWong, Rachel. _eeditor.
700	1		_aHuang, Eric. _eeditor.
700	1		_aHoogenraad, Casper. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9784431560487
856	4	0	_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-4-431-56050-0
912			_aZDB-2-SBL
942			_cLIBRO_ELEC
999			_c227187 _d227187