000 | 03906nam a22005655i 4500 | ||
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001 | 978-3-319-22708-5 | ||
003 | DE-He213 | ||
005 | 20180206183105.0 | ||
007 | cr nn 008mamaa | ||
008 | 151103s2016 gw | s |||| 0|eng d | ||
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_a9783319227085 _9978-3-319-22708-5 |
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_aPSA _2bicssc |
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_aSynthetic Biology _h[recurso electrónico] / _cedited by Anton Glieder, Christian P. Kubicek, Diethard Mattanovich, Birgit Wiltschi, Michael Sauer. |
250 | _a1st ed. 2016. | ||
264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2016. |
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300 |
_aVII, 368 p. 152 illus., 32 illus. in color. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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505 | 0 | _aXenobiotic life (artificial cells and cell like structures, biological nanostructures, XNA) -- Novel DNA and RNA (synthetic promoters, riboswitches, small RNAs, ribozymes, adaptamers, DNA walker, DNA machines) -- Expansion of the genetic code and protein building blocks (orthogonal mRNA-ribosome pairs, non canonical amino acids) -- DNA logics and circuit design (including sensors, TALORs, genome rewiring repressilator, oscillator, metabolator, ?Multicellular circuits?) -- Protein engineering (directed evolution, domain engineering) -- Synthetic metabolic pathways (engineered pathways, non natural pathways, scaffolding) -- Reengineered chassis cells (minimal organisms, platform hosts, minimal genomes, synthetic genomes) -- In silico simulation and design of complex metabolic and signalling networks -- Novel synthetic biomaterials -- Key methods for synthetic biology (assembly technologies, genome engineering technologies, DNA synthesis, Standardization) -- Public awareness and risk management. | |
520 | _aThe emergingfield of synthetic biology employs biotechnological approaches to recreate and enhance basic biological structures, intracellular processes and whole organisms. This book provides a comprehensive, up-to-date overview of the opportunities and challenges of this complex field of biotechnology, which combines various scientific disciplines. It addresses a broad range of topics, including redesigning complex metabolic pathways, DNA/RNA and protein engineering, as well as novel synthetic biomaterials. It discusses both ?bottom up? and ?top down? approaches and presents the latest genome engineering tools with predictions about how these could change our way of thinking and working. Since the use of synthetic biology raises a number of ethical questions, a chapter is devoted to public awareness and risk management. The book is of interest to scientists from both academia and industry, as well as PhD students and postdocs working in the field. | ||
650 | 0 | _aLife sciences. | |
650 | 0 | _aBiochemical engineering. | |
650 | 0 | _aGenetic engineering. | |
650 | 0 | _aSystems biology. | |
650 | 0 | _aBiomaterials. | |
650 | 1 | 4 | _aLife Sciences. |
650 | 2 | 4 | _aSystems Biology. |
650 | 2 | 4 | _aBiochemical Engineering. |
650 | 2 | 4 | _aBiomaterials. |
650 | 2 | 4 | _aGenetic Engineering. |
700 | 1 |
_aGlieder, Anton. _eeditor. |
|
700 | 1 |
_aKubicek, Christian P. _eeditor. |
|
700 | 1 |
_aMattanovich, Diethard. _eeditor. |
|
700 | 1 |
_aWiltschi, Birgit. _eeditor. |
|
700 | 1 |
_aSauer, Michael. _eeditor. |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9783319227078 |
856 | 4 | 0 |
_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-22708-5 |
912 | _aZDB-2-SBL | ||
942 | _cLIBRO_ELEC | ||
999 |
_c227241 _d227241 |