000			03213nam a22004935i 4500
001			978-3-319-26811-8
003			DE-He213
005			20180206183125.0
007			cr nn 008mamaa
008			151229s2016 gw | s |||| 0|eng d
020			_a9783319268118 _9978-3-319-26811-8
050		4	_aRM1-950
072		7	_aMMG _2bicssc
072		7	_aMED071000 _2bisacsh
082	0	4	_a615 _223
100	1		_aParimelazhagan, Thangaraj. _eauthor.
245	1	0	_aPharmacological Assays of Plant-Based Natural Products _h[recurso electrónico] / _cby Thangaraj Parimelazhagan.
264		1	_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2016.
300			_aXV, 188 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aProgress in Drug Research, _x0071-786X ; _v71
505	0		_a1. Extraction of plant material -- 2. Critical aspects of purification and impurities in natural product extracts. 3. In vitro antioxidant assays -- 4. In vivo antioxidant assays -- 5. Quantification assays -- 6. Anti-nutritional factors -- 7. Anti-inflammatory activity -- 8. Antipyretic activity -- 9. Inflammation bowel disease -- 10. Anti-arthritic activity -- 11. Evaluation of analgesic potential -- 12. Anti-diarrhoeal activity -- 13. Anti-ulcer activity -- 14. In vitro anti-diabetic activity -- 15. In vivo anti-diabetic activity -- 16. Hepatoprotective property -- 17. Antitumor activity -- 18. In vivo wound healing studies -- 19. Determination of cytotoxicity -- 20. Evaluation of bioavailability -- 21. Molecular identification by DNA barcoding -- 22. Molecular docking of bioactive compounds against BRCA and COX proteins.
520			_aThis volume provides information on how to select and screen plants for their medicinal properties. It describes phytopharmacological techniques for extracting and qualitatively and quantitatively analyzing a plant?s phytochemicals. After a detailed in vitro investigation including nutritional and anti-nutritional analyses, medicinal properties were tested with various in vivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer and anti-diabetic properties, as well as wound healing, neurodegenerative diseases, etc. Compound identification and purification techniques include, among others, TLC and column chromatography, as well as molecular docking with specific proteins.
650		0	_aMedicine.
650		0	_aPharmacology.
650		0	_aAnalytical chemistry.
650		0	_aPlant biochemistry.
650	1	4	_aBiomedicine.
650	2	4	_aPharmacology/Toxicology.
650	2	4	_aPlant Biochemistry.
650	2	4	_aAnalytical Chemistry.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783319268101
830		0	_aProgress in Drug Research, _x0071-786X ; _v71
856	4	0	_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-26811-8
912			_aZDB-2-SBL
942			_cLIBRO_ELEC
999			_c227609 _d227609