000 02728nam a22004335i 4500
001 978-3-319-45594-5
003 DE-He213
005 20180206183126.0
007 cr nn 008mamaa
008 161020s2016 gw | s |||| 0|eng d
020 _a9783319455945
_9978-3-319-45594-5
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
245 1 0 _aStrategies to Enhance the Therapeutic Ratio of Radiation as a Cancer Treatment
_h[recurso electrónico] /
_cedited by Mitchell S. Anscher, Kristoffer Valerie.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2016.
300 _aVI, 305 p. 65 illus., 53 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _a1. Mechanisms of Normal Tissue Response -- 2. The Role of Hypoxia in Radiation Response -- 3. The Role of Cancer Stem Cells in Tumour Radioresponse -- 4. Novel Strategies to Prevent, Mitigate or Reverse Radiation Injury and Fibrosis -- 5. Technology Based Strategies to Enhance the Therapeutic Ratio -- 6. Nitric Oxide Synthase Uncoupling in Tumor Progression and Cancer Therapy -- 7. Aiming the Immune System to Improve the Antitumor Efficacy of Radiation Therapy -- 8. The Role of MicroRNAs in modulating Tissue Response to Radiation -- 9. Adapting Therapy Based on Tumor Response -- 10. NQO1 Bioactivatable Drugs Modify Radiation Responses -- 11. DNA Repair Pathways as a Potential Target for Radiosensitization -- 12. Radiosensitizing Glioma by Targeting ATM with Small Molecule Inhibitors.
520 _aThis volume will describe recent progress and future directions in radiation oncology and biology research, focusing on strategies designed to improve disease control and reduce the risk of long-term adverse effects on patients. As more and more patients are becoming long-term survivors, this strategy will become increasingly important--in radiation oncology and throughout the field of oncology.
650 0 _aMedicine.
650 0 _aCancer research.
650 1 4 _aBiomedicine.
650 2 4 _aCancer Research.
700 1 _aAnscher, Mitchell S.
_eeditor.
700 1 _aValerie, Kristoffer.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319455921
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-45594-5
912 _aZDB-2-SBL
942 _cLIBRO_ELEC
999 _c227629
_d227629