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001 978-3-319-33145-4
003 DE-He213
005 20180206183133.0
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008 160423s2016 gw | s |||| 0|eng d
020 _a9783319331454
_9978-3-319-33145-4
050 4 _aQH573-671
072 7 _aPSF
_2bicssc
072 7 _aSCI049000
_2bisacsh
082 0 4 _a571.6
_223
100 1 _aKaranasios, Eleftherios.
_eauthor.
245 1 0 _aAutophagy at the Cell, Tissue and Organismal Level
_h[recurso electrónico] /
_cby Eleftherios Karanasios, Nicholas T. Ktistakis.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2016.
300 _aVI, 103 p. 15 illus., 12 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringerBriefs in Cell Biology
505 0 _aAutophagy (Autophagia) from 1860 to 1963 -- History of Autophagy after 1963 -- Signalling in Autophagy -- Autophagosome Formation -- Physiological Role of Autophagy and Implications in Disease -- Studying autophagy: List of useful antibodies produced via a community effort.
520 _aThis book provides an expert summary of autophagy, a relatively new but rapidly expanding field of biomedical science with important implications in health and disease. After a historical review ranging up to the identification of autophagy genes in mammals, the authors discuss the signaling pathways that regulate autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in development, ageing, neurodegeneration, immune function and cell differentiation. A comprehensive list of useful antibodies for studying autophagy compiled as a community effort is included at the end. The book is intended for newcomers to the field, as well as more experienced researchers looking for a condensed but comprehensive introduction to the physiological function and regulation of the autophagic pathway in mammalian organisms.
650 0 _aLife sciences.
650 0 _aImmunology.
650 0 _aBiochemistry.
650 0 _aCell biology.
650 1 4 _aLife Sciences.
650 2 4 _aCell Biology.
650 2 4 _aImmunology.
650 2 4 _aAnimal Biochemistry.
700 1 _aKtistakis, Nicholas T.
_eauthor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319331430
830 0 _aSpringerBriefs in Cell Biology
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-33145-4
912 _aZDB-2-SBL
942 _cLIBRO_ELEC
999 _c227785
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