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001			978-1-4939-6386-7
003			DE-He213
005			20180206183138.0
007			cr nn 008mamaa
008			161103s2016 xxu| s |||| 0|eng d
020			_a9781493963867 _9978-1-4939-6386-7
050		4	_aQP34-38
072		7	_aMFG _2bicssc
072		7	_aMED075000 _2bisacsh
082	0	4	_a612 _223
245	1	0	_aParental Obesity: Intergenerational Programming and Consequences _h[recurso electrónico] / _cedited by Lucy R. Green, Robert L. Hester.
264		1	_aNew York, NY : _bSpringer New York : _bImprint: Springer, _c2016.
300			_aXII, 389 p. 32 illus., 22 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aPhysiology in Health and Disease
505	0		_aWhy Obesity in Parents Matters -- Maternal obesity during pregnancy and cardio-metabolic development in the offspring -- Maternal obesity and gestational weight gain as determinants of long-term health -- Young maternal age, body composition and gestational intake impact pregnancy outcome: translational perspectives -- Maternal obesity and programming of the early embryo -- Paternal Obesity and Programming of Offspring Health -- The impact of maternal obesity and weight loss during the periconceptional period on offspring metabolism -- Mechanisms linking maternal obesity to offspring metabolic health -- The effect of maternal overnutrition on reward and anxiety in offspring -- The Implications of Maternal Obesity on Offspring Physiology and Behavior in the Non-human Primate -- The Impact of Maternal Obesity on Offspring Obesity via Programmed Adipogenesis and Appetite -- Developmental programming of non-alcoholic fatty liver disease (NAFLD) -- Maternal Metabolic State and Cancer Risk: An Evolving Manifestation of Generational Impact -- The influence of maternal obesity on offspring cardiovascular control and insights from rodent models -- Maternal obesity effects on the risk of allergic diseases in offspring -- Epigenetic mechanisms of maternal obesity effects on the descendants -- Early microbe contact in defining child metabolic health and obesity risk.
520			_aIn this book, leading figures in the field of Developmental Origins of Health and Disease provide up-to-date information from human clinical trials, cohorts, and animal physiology experiments to reveal the interdependence between parental obesity and health of the offspring. Obesity of the mother and father produces obesity in their offspring, so we are caught up in an intergenerational cycle, which means that even our children?s future health is in peril. This book gives a timely and much-needed synthesis of the mechanisms, potential targets of future interventions, and the challenges that need to be overcome in order to break the intergenerational cycle of obesity. This has profound implications for the way in which scientific, clinical and health policy activities are to be directed in order to combat the so-called epidemic of obesity, as well as diabetes, cancer and cardiovascular disease. The book will be of interest to students, clinicians, researchers and health policy makers who are either seeking an introduction to the area of Developmental Origins of Health and Disease or have a specific interest in the pathogenesis of obesity.
650		0	_aMedicine.
650		0	_aGene expression.
650		0	_aHuman physiology.
650		0	_aHealth promotion.
650		0	_aMaternal and child health services.
650		0	_aAnimal physiology.
650	1	4	_aBiomedicine.
650	2	4	_aHuman Physiology.
650	2	4	_aAnimal Physiology.
650	2	4	_aGene Expression.
650	2	4	_aMaternal and Child Health.
650	2	4	_aHealth Promotion and Disease Prevention.
700	1		_aGreen, Lucy R. _eeditor.
700	1		_aHester, Robert L. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781493963843
830		0	_aPhysiology in Health and Disease
856	4	0	_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-1-4939-6386-7
912			_aZDB-2-SBL
942			_cLIBRO_ELEC
999			_c227874 _d227874