000 03682nam a22005535i 4500
001 978-3-319-78127-3
003 DE-He213
005 20210201191310.0
007 cr nn 008mamaa
008 180828s2018 gw | s |||| 0|eng d
020 _a9783319781273
_9978-3-319-78127-3
050 4 _aQR180-189.5
072 7 _aMJCM
_2bicssc
072 7 _aMED044000
_2bisacsh
072 7 _aMJCM
_2thema
082 0 4 _a616.079
_223
245 1 0 _aStromal Immunology
_h[electronic resource] /
_cedited by Benjamin M.J Owens, Matthew A. Lakins.
250 _a1st ed. 2018.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2018.
300 _aXIII, 151 p. 15 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v1060
500 _aAcceso multiusuario
505 0 _aLeukocyte-Stromal Interactions within Lymph Nodes -- Stromal Cell Responses in Infection -- Fibroblasts and Osteoblasts in Inflammation and Bone Damage -- Molecular and Cellular Requirements for Tertiary Lymphoid Organs -- Molecular and Cellular Requirements for Tertiary Lymphoid Organs -- Mesenchymal Stem Cells as Endogenous Regulators of Inflammation -- Stromal cells in the Tumor Microenvironment II -- Immunosuppression by Intestinal Stromal Cells -- Novel models to Study Stromal Cell Leukocyte Interactions in Health and Disease.
520 _aResearch into and interest in the role of stromal cells in immunology has exploded over the past 15 years. The conventional view that placed non-hematopoietic stromal cells as passive, structural, and supportive entities has now been replaced with an appreciation that these cells have active, dynamic roles during immune responses, and thus impact on the pathophysiology of multiple immune-mediated diseases. This book serves to provide solid grounding in the fundamentals of stromal immunology, focusing on the biological aspects of their function in addition to highlighting key areas for the development of the field in the future. The book is also a unique source of information on emerging concepts that place stromal cells from outside lymphoid organs as major contributors to the biology of diverse conditions, such as rheumatoid arthritis, chronic parasitic infection, inflammatory bowel disease, and cancer.
541 _fUABC ;
_cTemporal ;
_d01/01/2021-12/31/2023.
650 0 _aImmunology.
650 0 _aCell biology.
650 1 4 _aImmunology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B14000
650 2 4 _aCell Biology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/L16008
700 1 _aOwens, Benjamin M.J.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aLakins, Matthew A.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783319781259
776 0 8 _iPrinted edition:
_z9783319781266
776 0 8 _iPrinted edition:
_z9783030086213
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v1060
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-78127-3
912 _aZDB-2-SBL
912 _aZDB-2-SXB
942 _cLIBRO_ELEC
999 _c241854
_d241853