000 | 03682nam a22005535i 4500 | ||
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001 | 978-3-319-78127-3 | ||
003 | DE-He213 | ||
005 | 20210201191310.0 | ||
007 | cr nn 008mamaa | ||
008 | 180828s2018 gw | s |||| 0|eng d | ||
020 |
_a9783319781273 _9978-3-319-78127-3 |
||
050 | 4 | _aQR180-189.5 | |
072 | 7 |
_aMJCM _2bicssc |
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072 | 7 |
_aMED044000 _2bisacsh |
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_aMJCM _2thema |
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_a616.079 _223 |
245 | 1 | 0 |
_aStromal Immunology _h[electronic resource] / _cedited by Benjamin M.J Owens, Matthew A. Lakins. |
250 | _a1st ed. 2018. | ||
264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2018. |
|
300 |
_aXIII, 151 p. 15 illus. in color. _bonline resource. |
||
336 |
_atext _btxt _2rdacontent |
||
337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
||
490 | 1 |
_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v1060 |
|
500 | _aAcceso multiusuario | ||
505 | 0 | _aLeukocyte-Stromal Interactions within Lymph Nodes -- Stromal Cell Responses in Infection -- Fibroblasts and Osteoblasts in Inflammation and Bone Damage -- Molecular and Cellular Requirements for Tertiary Lymphoid Organs -- Molecular and Cellular Requirements for Tertiary Lymphoid Organs -- Mesenchymal Stem Cells as Endogenous Regulators of Inflammation -- Stromal cells in the Tumor Microenvironment II -- Immunosuppression by Intestinal Stromal Cells -- Novel models to Study Stromal Cell Leukocyte Interactions in Health and Disease. | |
520 | _aResearch into and interest in the role of stromal cells in immunology has exploded over the past 15 years. The conventional view that placed non-hematopoietic stromal cells as passive, structural, and supportive entities has now been replaced with an appreciation that these cells have active, dynamic roles during immune responses, and thus impact on the pathophysiology of multiple immune-mediated diseases. This book serves to provide solid grounding in the fundamentals of stromal immunology, focusing on the biological aspects of their function in addition to highlighting key areas for the development of the field in the future. The book is also a unique source of information on emerging concepts that place stromal cells from outside lymphoid organs as major contributors to the biology of diverse conditions, such as rheumatoid arthritis, chronic parasitic infection, inflammatory bowel disease, and cancer. | ||
541 |
_fUABC ; _cTemporal ; _d01/01/2021-12/31/2023. |
||
650 | 0 | _aImmunology. | |
650 | 0 | _aCell biology. | |
650 | 1 | 4 |
_aImmunology. _0https://scigraph.springernature.com/ontologies/product-market-codes/B14000 |
650 | 2 | 4 |
_aCell Biology. _0https://scigraph.springernature.com/ontologies/product-market-codes/L16008 |
700 | 1 |
_aOwens, Benjamin M.J. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt |
|
700 | 1 |
_aLakins, Matthew A. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer Nature eBook | |
776 | 0 | 8 |
_iPrinted edition: _z9783319781259 |
776 | 0 | 8 |
_iPrinted edition: _z9783319781266 |
776 | 0 | 8 |
_iPrinted edition: _z9783030086213 |
830 | 0 |
_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v1060 |
|
856 | 4 | 0 |
_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-78127-3 |
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942 | _cLIBRO_ELEC | ||
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