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001 978-3-319-89506-2
003 DE-He213
005 20210201191313.0
007 cr nn 008mamaa
008 180720s2018 gw | s |||| 0|eng d
020 _a9783319895062
_9978-3-319-89506-2
050 4 _aQP356.3
072 7 _aMJN
_2bicssc
072 7 _aMED057000
_2bisacsh
072 7 _aMKJ
_2thema
082 0 4 _a612.8042
_223
245 1 0 _aTextbook of Energy Balance, Neuropeptide Hormones, and Neuroendocrine Function
_h[electronic resource] /
_cedited by Eduardo A. Nillni.
250 _a1st ed. 2018.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2018.
300 _aXIV, 378 p. 49 illus., 47 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
500 _aAcceso multiusuario
505 0 _a1. The Evolution from Lean to Obese State and the Influence of Modern Human Society -- 2. Neuropeptides Controlling Our Behavior -- 3. Transcriptional Regulation of Hypothalamic Energy Balance Genes -- 4. Brain Inflammation and Endoplasmic Reticulum Stress -- 5. The Cell Biology of Neuropeptide Hormones -- 6. Nutrient Sensors Regulating Peptides -- 7. Gatrointestinal Hormones Controlling Energy Homeostasis and Their Potential Role in Obesity -- 8. The Complexity of Adipose Tissue -- 9. Adipokines, Inflammation and Insulin Resistance in Obesity -- 10. The Thyroid Hormone Axis: Its Roles in Body Weight Regulation, Obesity and Weight Loss -- 11. Obesity and Stress: The Melanocortin Connection -- 12. Obesity and the Growth Hormone Axis -- 13. Brain, Environment, Hormone-Based in of Appetite, Ingestive Behavior, and Body Weight.
520 _aThis textbook presents for the first time a comprehensive body of the latest knowledge in the field of neuropeptides and their action on energy balance. It contains a detailed and comprehensive account of the specific hypothalamic peptides in regards to their roles in energy balance, food intake control and co-morbidities, to better understand the patho-physiology of obesity. The textbook includes an examination the history of the evolution of human society from a thin to the obese phenotype and, within that context, how modern society habits and industrial food production did not respect the evolutionary trait resulting in changes in the energy balance set point. It provides a novel conceptualization of the problem of obesity when considering the biochemistry of peptide hormones and entertaining novel ideas on multiple approaches to the problems of energy balance, as well as demonstrates and explains why alterations in pro-hormone processing are paramount to understand metabolic disease. This text is excellent material for teaching graduate and medical school courses, as well as a valuable resource for researchers in biochemistry, cell, and molecular biology, neuroscientists, physician endocrinologists, and nutritionists.
541 _fUABC ;
_cTemporal ;
_d01/01/2021-12/31/2023.
650 0 _aNeurochemistry.
650 0 _aEndocrinology .
650 0 _aHuman physiology.
650 1 4 _aNeurochemistry.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B18010
650 2 4 _aEndocrinology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/H33053
650 2 4 _aHuman Physiology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B13004
700 1 _aNillni, Eduardo A.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783319895055
776 0 8 _iPrinted edition:
_z9783319895079
776 0 8 _iPrinted edition:
_z9783030077877
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-89506-2
912 _aZDB-2-SBL
912 _aZDB-2-SXB
942 _cLIBRO_ELEC
999 _c241922
_d241921