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020 _a9783319941745
_9978-3-319-94174-5
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072 7 _aTGMT
_2bicssc
072 7 _aTEC021000
_2bisacsh
072 7 _aTGMT
_2thema
082 0 4 _a620.11
_223
245 1 0 _aParticles and Nanoparticles in Pharmaceutical Products
_h[electronic resource] :
_bDesign, Manufacturing, Behavior and Performance /
_cedited by Henk G. Merkus, Gabriel M. H. Meesters, Wim Oostra.
250 _a1st ed. 2018.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2018.
300 _aXII, 446 p. 110 illus., 46 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAAPS Advances in the Pharmaceutical Sciences Series,
_x2210-7371 ;
_v29
500 _aAcceso multiusuario
505 0 _aPreface -- Author Information -- Introduction -- Guide to Pharmaceutical Product Quality -- Bio-Nano: Theranostic at Cellular Level -- Moving Liposome Technology from the Bench to the Oncological Patient: Towards Performance by Design -- Fundamentals of Dry Powder Inhaler Technology -- Blending and Characterization of Pharmaceutical Powders -- Guidance on Drug Substance Particle Size Controls -- Effects of Particle Size, Surface Nature and Crystal Type on Dissolution Rate -- Amorphous APIs: Improved Release, Preparation, Characterization -- Particle Properties: Impact on the Processing and Performance of Oral Extended-Release Hydrophilic Matrix Tablets -- The Role of Particulates in Film Coating of Pharmaceutical Tablets -- Particulates in Semi-solid Pharmaceutical Products -- The Side Effects of Drugs: Nanopathological Hazards and Risks -- Subject Index. .
520 _aThis edited volume brings together the expertise of numerous specialists on the topic of particles - their physical, chemical, pharmacological and toxicological characteristics - when they are a component of pharmaceutical products and formulations. The book discusses in detail properties such as the composition, size, shape, surface properties and porosity of particles with respect to how they impact the formulations and products in which they are used and the effective delivery of pharmaceutical active ingredients. It considers all dosage forms of pharmaceuticals involving particles, from powders to tablets, creams to ointments, and solutions to dry-powder inhalers, also including the latest nanomedicine products. Further, it discusses examples of particle toxicity, as well as the important subject of pharmaceutical industry regulations, guidelines and legislation. The book is of interest to researchers and practitioners who work on testing and developing pharmaceutical dosage and delivery systems.
541 _fUABC ;
_cTemporal ;
_d01/01/2021-12/31/2023.
650 0 _aMaterials science.
650 0 _aPharmaceutical technology.
650 0 _aChemical engineering.
650 0 _aNanotechnology.
650 0 _aNanochemistry.
650 1 4 _aCharacterization and Evaluation of Materials.
_0https://scigraph.springernature.com/ontologies/product-market-codes/Z17000
650 2 4 _aPharmaceutical Sciences/Technology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B21010
650 2 4 _aIndustrial Chemistry/Chemical Engineering.
_0https://scigraph.springernature.com/ontologies/product-market-codes/C27000
650 2 4 _aNanotechnology and Microengineering.
_0https://scigraph.springernature.com/ontologies/product-market-codes/T18000
650 2 4 _aNanochemistry.
_0https://scigraph.springernature.com/ontologies/product-market-codes/C33000
700 1 _aMerkus, Henk G.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aMeesters, Gabriel M. H.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aOostra, Wim.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783319941738
776 0 8 _iPrinted edition:
_z9783319941752
776 0 8 _iPrinted edition:
_z9783030068097
830 0 _aAAPS Advances in the Pharmaceutical Sciences Series,
_x2210-7371 ;
_v29
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-94174-5
912 _aZDB-2-SBL
912 _aZDB-2-SXB
942 _cLIBRO_ELEC
999 _c242031
_d242030