000 | 05024nam a22005655i 4500 | ||
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001 | 978-3-319-95390-8 | ||
003 | DE-He213 | ||
005 | 20210201191321.0 | ||
007 | cr nn 008mamaa | ||
008 | 181024s2018 gw | s |||| 0|eng d | ||
020 |
_a9783319953908 _9978-3-319-95390-8 |
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050 | 4 | _aRM1-950 | |
072 | 7 |
_aMMG _2bicssc |
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072 | 7 |
_aMED071000 _2bisacsh |
|
072 | 7 |
_aMKG _2thema |
|
082 | 0 | 4 |
_a615 _223 |
245 | 1 | 0 |
_aSelenium _h[electronic resource] / _cedited by Bernhard Michalke. |
250 | _a1st ed. 2018. | ||
264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2018. |
|
300 |
_aXV, 522 p. 57 illus., 28 illus. in color. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
||
490 | 1 |
_aMolecular and Integrative Toxicology, _x2168-4219 |
|
500 | _aAcceso multiusuario | ||
505 | 0 | _aPart I - Overview: 1. Selenium in Human Health and Disease: an Overview -- Part II - Bioaccessibility and Dietary Aspects of Selenium: 2. Selenium in Soils and Crops -- 3. Dietary Aspects for Selenium and/or Selenium Compounds -- Part III - Genes, Proteins, Pathways, and Metabolism Related to Selenium: 4. Contribution of the Yeast Saccharomyces Cerevisiae Model to Understand the Mechanisms of Selenium Toxicity -- 5. Selenium Metabolism, Regulation And Sex Differences In Mammals -- Part IV - The Role of Selenium within Redox System, Inflammation, and Thyroid Interaction: 6. Oxidative Stress, Selenium Redox Systems Including GPX / TXNRD Families -- 7. Selenium and Inflammatory Mediators -- 8. Selenium and Thyroid Function -- Part V - The Role of Selenium in Neurodevelopment and Neurological Disorders: 9. Selenium and Neurodevelopment -- 10. Selenium and Autism Spectrum Disorder -- 11. Selenium in Ischemic Stroke -- 12. Selenium neurotoxicity and Amyotrophic Lateral Sclerosis: An Epidemiologic Perspective -- Part VI - The Role of Selenium in Cancer: 13. Therapeutic Potential of Selenium Compounds in the Treatment of Cancer -- 14. Selenocystine and Cancer -- 15. Selenium in Radiation Oncology -- Part VII - The Role of Selenium in Various Diseases and Health Issues: 16. Selenium and Cardiovascular Disease: Epidemiological Evidence of a Possible U-Shaped Relationship -- 17. Selenium and Diabetes -- 18. Uncovering the Importance of Selenium in Muscle Disease -- 19. Selenium in Immune Response and Intensive Care -- 20. Selenium and Toxicological Aspects: Cytotoxicity, Cellular Bioavailability and Biotransformation of Se-Species -- 21. Selenium Nanoparticles - Biomedical Application -- 22. Selenium Interactions with Other Trace Elements, with Nutrients (and Drugs) in Humans -- Part VIII - Selenium Analytics, Speciation and Biomonitoring: 23. Biomarkers of Selenium Status -- 24. Human Biomonitoring of Selenium Exposure -- 25. Bioanalytical Chemistry of Selenium. | |
520 | _aThis book summarizes the fast-growing and current knowledge about selenium interaction with cancer, diabetes, neuro-degeneration, heart disease, muscle disorders, HIV and several more. A special focus will be placed on in-depth knowledge about gene expression, selenoprotein biosynthesis, seleno-metabolism--as well as the molecular pathways, physiological roles, and the molecular action of selenium including interaction with other elements and vitamins or as Se-nanoparticles. The reader will receive the newest information regarding redox status and redox regulatory systems, specifically in relation to different glutathione peroxidases and thioredoxin-reductases as well as about cellular bioavailability and cytotoxicity, de-balanced immune response, inflammation or dietary aspects. | ||
541 |
_fUABC ; _cTemporal ; _d01/01/2021-12/31/2023. |
||
650 | 0 | _aPharmacology. | |
650 | 0 | _aMedical biochemistry. | |
650 | 0 | _aMolecular biology. | |
650 | 1 | 4 |
_aPharmacology/Toxicology. _0https://scigraph.springernature.com/ontologies/product-market-codes/B21007 |
650 | 2 | 4 |
_aMedical Biochemistry. _0https://scigraph.springernature.com/ontologies/product-market-codes/H35005 |
650 | 2 | 4 |
_aMolecular Medicine. _0https://scigraph.springernature.com/ontologies/product-market-codes/B1700X |
700 | 1 |
_aMichalke, Bernhard. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer Nature eBook | |
776 | 0 | 8 |
_iPrinted edition: _z9783319953892 |
776 | 0 | 8 |
_iPrinted edition: _z9783319953915 |
776 | 0 | 8 |
_iPrinted edition: _z9783030070267 |
830 | 0 |
_aMolecular and Integrative Toxicology, _x2168-4219 |
|
856 | 4 | 0 |
_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-95390-8 |
912 | _aZDB-2-SBL | ||
912 | _aZDB-2-SXB | ||
942 | _cLIBRO_ELEC | ||
999 |
_c242077 _d242076 |