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001 | 978-981-13-0484-2 | ||
003 | DE-He213 | ||
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007 | cr nn 008mamaa | ||
008 | 180720s2018 si | s |||| 0|eng d | ||
020 |
_a9789811304842 _9978-981-13-0484-2 |
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_a616.9101 _223 |
245 | 1 | 0 |
_aHIV Vaccines and Cure _h[electronic resource] : _bThe Path Towards Finding an Effective Cure and Vaccine / _cedited by Linqi Zhang, Sharon R. Lewin. |
250 | _a1st ed. 2018. | ||
264 | 1 |
_aSingapore : _bSpringer Singapore : _bImprint: Springer, _c2018. |
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300 |
_aXV, 318 p. 21 illus., 16 illus. in color. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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490 | 1 |
_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v1075 |
|
500 | _aAcceso multiusuario | ||
505 | 0 | _aHIV Vaccine Efficacy Trials: RV144 and beyond -- HIV T-cell vaccines -- HIV broadly neutralizing antibodies: VRC01 and beyond -- Structural features of broadly neutralizing antibodies and rational design of vaccine -- Monkey models and HIV vaccine research -- Treatment of HIV for the Prevention of Transmission in Discordant Couples and at the Population Level -- HIV persistence on antiretroviral therapy and barriers to a cure -- The molecular biology of HIV latency -- Cellular determinants of HIV persistence on antiretroviral therapy -- In Vitro and In Vivo Models of HIV Latency -- Measuring HIV persistence on antiretroviral therapy -- Clinical interventions in HIV cure research. | |
520 | _aThis book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry. | ||
541 |
_fUABC ; _cTemporal ; _d01/01/2021-12/31/2023. |
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650 | 0 | _aVirology. | |
650 | 0 | _aVaccines. | |
650 | 0 | _aImmunology. | |
650 | 0 | _aAnimal models in research. | |
650 | 1 | 4 |
_aVirology. _0https://scigraph.springernature.com/ontologies/product-market-codes/B22003 |
650 | 2 | 4 |
_aVaccine. _0https://scigraph.springernature.com/ontologies/product-market-codes/B16010 |
650 | 2 | 4 |
_aImmunology. _0https://scigraph.springernature.com/ontologies/product-market-codes/B14000 |
650 | 2 | 4 |
_aAnimal Models. _0https://scigraph.springernature.com/ontologies/product-market-codes/L25050 |
700 | 1 |
_aZhang, Linqi. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt |
|
700 | 1 |
_aLewin, Sharon R. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer Nature eBook | |
776 | 0 | 8 |
_iPrinted edition: _z9789811304835 |
776 | 0 | 8 |
_iPrinted edition: _z9789811304859 |
776 | 0 | 8 |
_iPrinted edition: _z9789811344282 |
830 | 0 |
_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v1075 |
|
856 | 4 | 0 |
_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-981-13-0484-2 |
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