000 | 03974nam a22005895i 4500 | ||
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001 | 978-3-319-74932-7 | ||
003 | DE-He213 | ||
005 | 20210201191328.0 | ||
007 | cr nn 008mamaa | ||
008 | 180406s2018 gw | s |||| 0|eng d | ||
020 |
_a9783319749327 _9978-3-319-74932-7 |
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050 | 4 | _aQH506 | |
072 | 7 |
_aMBGR _2bicssc |
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_aSCI049000 _2bisacsh |
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_aMBGR _2thema |
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_aPSD _2thema |
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_a611.01816 _223 |
245 | 1 | 0 |
_aMetabolic Interaction in Infection _h[electronic resource] / _cedited by Ricardo Silvestre, Egídio Torrado. |
250 | _a1st ed. 2018. | ||
264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2018. |
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300 |
_aVIII, 476 p. 45 illus., 43 illus. in color. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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490 | 1 |
_aExperientia Supplementum, _x1664-431X ; _v109 |
|
500 | _aAcceso multiusuario | ||
505 | 0 | _aPart I: A guide of metabolism during host-pathogen interactions -- 1. Cellular metabolism at a glance -- 2. Interaction between nutrition and metabolism -- 3. Interplay between metabolic sensors and cell signaling -- 4. Alterations on cellular redox states upon infection and implications for host cell homeostasis -- 5. Mitochondrial bioenergetics and dynamics during infection -- 6. Computational systems biology of metabolism in infection -- 7. Metabolomic-based methods in diagnosis and monitoring infection progression -- Part II: Microbial metabolic adaptation and pathogen rewiring of host cell metabolism during infection -- 8. Metabolic host response to intracellular infections -- 9. Protozoan parasites auxotrophies and metabolic dependencies -- 10. Viral manipulation of the host metabolic network -- 11. Metabolic regulation of innate immunity to fungal infection -- 12. Metabolic crosstalk between host and parasitic pathogens -- 13. Microbiome and gut dysbiosis. | |
520 | _aThis book focuses on host-pathogen interactions at the metabolic level. It explores the metabolic requirements of the infectious agents, the microbial metabolic pathways that are dedicated to circumvent host immune mechanisms as well as the molecular mechanisms by which pathogens hijack host cell metabolism for their own benefit. Finally, it provides insights on the possible clinical and immunotherapeutic applications, as well as on the available experimental and analytical methods. The contributions break new ground in understanding the metabolic crosstalk between host and pathogen. | ||
541 |
_fUABC ; _cTemporal ; _d01/01/2021-12/31/2023. |
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650 | 0 | _aMolecular biology. | |
650 | 0 | _aBiochemistry. | |
650 | 0 | _aMedical microbiology. | |
650 | 1 | 4 |
_aMolecular Medicine. _0https://scigraph.springernature.com/ontologies/product-market-codes/B1700X |
650 | 2 | 4 |
_aBiochemistry, general. _0https://scigraph.springernature.com/ontologies/product-market-codes/L14005 |
650 | 2 | 4 |
_aMedical Microbiology. _0https://scigraph.springernature.com/ontologies/product-market-codes/B16003 |
700 | 1 |
_aSilvestre, Ricardo. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt |
|
700 | 1 |
_aTorrado, Egídio. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer Nature eBook | |
776 | 0 | 8 |
_iPrinted edition: _z9783319749310 |
776 | 0 | 8 |
_iPrinted edition: _z9783319749334 |
776 | 0 | 8 |
_iPrinted edition: _z9783030091088 |
830 | 0 |
_aExperientia Supplementum, _x1664-431X ; _v109 |
|
856 | 4 | 0 |
_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-74932-7 |
912 | _aZDB-2-SBL | ||
912 | _aZDB-2-SXB | ||
942 | _cLIBRO_ELEC | ||
999 |
_c242204 _d242203 |