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007 cr nn 008mamaa
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020 _a9783319749327
_9978-3-319-74932-7
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072 7 _aMBGR
_2bicssc
072 7 _aSCI049000
_2bisacsh
072 7 _aMBGR
_2thema
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082 0 4 _a611.01816
_223
245 1 0 _aMetabolic Interaction in Infection
_h[electronic resource] /
_cedited by Ricardo Silvestre, Egídio Torrado.
250 _a1st ed. 2018.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2018.
300 _aVIII, 476 p. 45 illus., 43 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aExperientia Supplementum,
_x1664-431X ;
_v109
500 _aAcceso multiusuario
505 0 _aPart I: A guide of metabolism during host-pathogen interactions -- 1. Cellular metabolism at a glance -- 2. Interaction between nutrition and metabolism -- 3. Interplay between metabolic sensors and cell signaling -- 4. Alterations on cellular redox states upon infection and implications for host cell homeostasis -- 5. Mitochondrial bioenergetics and dynamics during infection -- 6. Computational systems biology of metabolism in infection -- 7. Metabolomic-based methods in diagnosis and monitoring infection progression -- Part II: Microbial metabolic adaptation and pathogen rewiring of host cell metabolism during infection -- 8. Metabolic host response to intracellular infections -- 9. Protozoan parasites auxotrophies and metabolic dependencies -- 10. Viral manipulation of the host metabolic network -- 11. Metabolic regulation of innate immunity to fungal infection -- 12. Metabolic crosstalk between host and parasitic pathogens -- 13. Microbiome and gut dysbiosis.
520 _aThis book focuses on host-pathogen interactions at the metabolic level. It explores the metabolic requirements of the infectious agents, the microbial metabolic pathways that are dedicated to circumvent host immune mechanisms as well as the molecular mechanisms by which pathogens hijack host cell metabolism for their own benefit. Finally, it provides insights on the possible clinical and immunotherapeutic applications, as well as on the available experimental and analytical methods. The contributions break new ground in understanding the metabolic crosstalk between host and pathogen.
541 _fUABC ;
_cTemporal ;
_d01/01/2021-12/31/2023.
650 0 _aMolecular biology.
650 0 _aBiochemistry.
650 0 _aMedical microbiology.
650 1 4 _aMolecular Medicine.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B1700X
650 2 4 _aBiochemistry, general.
_0https://scigraph.springernature.com/ontologies/product-market-codes/L14005
650 2 4 _aMedical Microbiology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B16003
700 1 _aSilvestre, Ricardo.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aTorrado, Egídio.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783319749310
776 0 8 _iPrinted edition:
_z9783319749334
776 0 8 _iPrinted edition:
_z9783030091088
830 0 _aExperientia Supplementum,
_x1664-431X ;
_v109
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-74932-7
912 _aZDB-2-SBL
912 _aZDB-2-SXB
942 _cLIBRO_ELEC
999 _c242204
_d242203