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001 978-3-319-97367-8
003 DE-He213
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007 cr nn 008mamaa
008 180926s2018 gw | s |||| 0|eng d
020 _a9783319973678
_9978-3-319-97367-8
050 4 _aQR180-189.5
072 7 _aMJCM
_2bicssc
072 7 _aMED044000
_2bisacsh
072 7 _aMJCM
_2thema
082 0 4 _a616.079
_223
245 1 0 _aUnderstanding the Host Immune Response Against Mycobacterium tuberculosis Infection
_h[electronic resource] /
_cedited by Vishwanath Venketaraman.
250 _a1st ed. 2018.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2018.
300 _aX, 144 p. 14 illus., 12 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
500 _aAcceso multiusuario
505 0 _a1. Co-Morbidities in HIV and Tuberculosis. Elizabeth Luke Hanna, Dept of Clinical Research, National institute for Research in TB, India -- 2. Diabetes and Tuberculosis. Blanca Restrepo, Dept. of Microbiology, Immunology, Molecular Genetics, UT Health - San Antonio -- 3. Extrapulmonary Tuberculosis. Johan Feuth Schoeman, Dept of Neurology, University of Stellenbosch -- 4. Animal Models to Study Adaptive Immune Responses Against M. tb Infection. Janice J. Endsley, Dept of Pathology, UT Medical Branch -- 5. Immunodiagnosis of Tuberculosis. Keertan Dheda, Dept of Respiratory Medicine, University of Cape Town -- 6. Granulomatous Responses Against M. tb Infection. Selvakumar Subbian, Dept of Biomedical and Health Sciences, Rutgers University -- 7. Host-Directed Therapies for Tuberculosis. Vishwanath Venketaraman (editor).
520 _aAccording to the World Health Organization, approximately one third of the world's population is latently infected with Mycobacterium tuberculosis (M. tb [LTBI]), of whom about 9 million have active tuberculosis (TB). It is estimated that approximately 2 million individuals die each year from active TB. An estimated 14.4% of these individuals have HIV and M. tb co-infection. TB has long been known to be one of the leading causes of death in HIV-infected individuals. Recent evidence now indicates that individuals with type 2 diabetes, the elderly, and chronic smokers are also increasingly susceptible to TB infection, the ability of their immune system to fight off active TB infection having been compromised by their condition. This book therefore aims to provide a detailed review of recent advances in the research that involves characterizing the host's immune responses against TB infection in conditions such as HIV, diabetes, chronic cigarette smoking and aging, and strategies to restore favorable immune responses against this deadly pathogen.
541 _fUABC ;
_cTemporal ;
_d01/01/2021-12/31/2023.
650 0 _aImmunology.
650 0 _aInfectious diseases.
650 1 4 _aImmunology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B14000
650 2 4 _aInfectious Diseases.
_0https://scigraph.springernature.com/ontologies/product-market-codes/H33096
700 1 _aVenketaraman, Vishwanath.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783319973661
776 0 8 _iPrinted edition:
_z9783319973685
776 0 8 _iPrinted edition:
_z9783030073442
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-97367-8
912 _aZDB-2-SBL
912 _aZDB-2-SXB
942 _cLIBRO_ELEC
999 _c242296
_d242295