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082 0 4 _a570.285
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100 1 _aSaitou, Naruya.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
245 1 0 _aIntroduction to Evolutionary Genomics
_h[electronic resource] /
_cby Naruya Saitou.
250 _a2nd ed. 2018.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2018.
300 _aXXV, 504 p. 234 illus., 38 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
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490 1 _aComputational Biology,
_x1568-2684 ;
_v17
500 _aAcceso multiusuario
505 0 _aPart I: Basic Processes of Genome Evolution -- Replication, Transcription, and Translation -- Proteins -- Mutation -- Phylogeny -- Neutral Evolution -- Natural Selection -- Part II: Evolving Genomes -- A Brief History of Life -- Prokaryote Genomes -- Eukaryote Genomes -- Virus Genomes -- Vertebrate Genomes -- The Human Genome -- Part III: Methods for Evolutionary Genomics -- Genome and Transcriptome Sequencing -- Omic Worlds and their Databases -- Homology Search and Multiple Alignment -- Evolutionary Distances -- Phylogeny Construction -- Human Population Genomics.
520 _aThis authoritative textbook/reference presents a comprehensive introduction to the field of evolutionary genomics. The opening chapters describe the fundamental concepts in molecular biology and genome evolution for readers without any prior background in this area. This is followed by a detailed examination of genome evolution in various different groups of organisms. The text then concludes with a review of practical methods essential to researchers in the field. This updated and revised new edition also features historical perspectives on contributions to evolutionary genomics from related fields such as molecular evolution, genetics, and numerical taxonomy. Topics and features: Introduces the basics of molecular biology, covering protein structure and diversity, as well as DNA replication, transcription, and translation Examines the phylogenetic relationships of DNA sequences, and the processes of mutation, neutral evolution, and natural selection Presents a brief evolutionary history of life, surveying the key features of the genomes of prokaryotes, eukaryotes, viruses and phages, vertebrates, and humans Reviews the various biological "omic" databases, and discusses the analysis of homologous nucleotide and amino acid sequences Provides an overview of the experimental sequencing of genomes and transcriptomes, and the construction of phylogenetic trees Describes methods for estimating of evolutionary distances, and performing studies of population genetics Supplies additional supporting material at an associated website Serving as an indispensable textbook for graduate and advanced undergraduate courses on evolutionary genomics, this accessible overview will also prove invaluable to researchers from both computer science and the biological sciences seeking a primer on the field. Dr. Naruya Saitou is a Professor in the Division of Population Genetics at the National Institute of Genetics, and a Professor in the Department of Genetics at the Graduate University for Advanced Studies, Mishima, Japan. He is also a Professor in the Department of Biological Sciences at the University of Tokyo, Japan.
541 _fUABC ;
_cTemporal ;
_d01/01/2021-12/31/2023.
650 0 _aBioinformatics.
650 0 _aSystems biology.
650 0 _aMicrobial genetics.
650 0 _aMicrobial genomics.
650 0 _aPlant genetics.
650 0 _aAnimal genetics.
650 1 4 _aComputational Biology/Bioinformatics.
_0https://scigraph.springernature.com/ontologies/product-market-codes/I23050
650 2 4 _aSystems Biology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/L15010
650 2 4 _aMicrobial Genetics and Genomics.
_0https://scigraph.springernature.com/ontologies/product-market-codes/L32010
650 2 4 _aPlant Genetics and Genomics.
_0https://scigraph.springernature.com/ontologies/product-market-codes/L32020
650 2 4 _aAnimal Genetics and Genomics.
_0https://scigraph.springernature.com/ontologies/product-market-codes/L32030
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783319926414
776 0 8 _iPrinted edition:
_z9783319926438
776 0 8 _iPrinted edition:
_z9783030064785
830 0 _aComputational Biology,
_x1568-2684 ;
_v17
856 4 0 _zLibro electrónico
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