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020 _a9783319964454
_9978-3-319-96445-4
050 4 _aR857.T55
072 7 _aPSF
_2bicssc
072 7 _aSCI049000
_2bisacsh
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_2thema
082 0 4 _a612.028
_223
082 0 4 _a571.538
_223
245 1 0 _aMolecular, Cellular, and Tissue Engineering of the Vascular System
_h[electronic resource] /
_cedited by Bingmei M. Fu, Neil T. Wright.
250 _a1st ed. 2018.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2018.
300 _aVIII, 334 p. 84 illus., 65 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v1097
500 _aAcceso multiusuario
505 0 _aChapter 1: The Role of Endothelial Surface Glycocalyx in Mechanosensing and Transduction -- Chapter 2: The Molecular Structure Of The Endothelial Gycocalyx Layer (EGL) and Surface Layers (ESL) Modulation of Transvascular Exchange -- Chapter 3: Role of the Glycocalyx as a Barrier to Leukocyte-Endothelium Adhesion -- Chapter 4: Mechanobiology and Vascular Remodeling: from Membrane to Nucleus -- Chapter 5: Endothelial nuclear lamina in mechanotransduction under shear stress -- Chapter 6: Regional heterogeneity in the regulation of vasoconstriction in arteries and its role in vascular mechanics -- Chapter 7: Microcalcifications, their genesis, growth and biomechanical stability in fibrous cap rupture -- Chapter 8: Abdominal Aortic Aneurysm Pathomechanics: Current Understanding and Future Directions -- Chapter 9: Vascular intervention: from angioplasty to bioresorbable vascular scaffold -- Chapter 10: On the physics underlying longitudinal capillary recruitment -- Chapter 11: Tumor Metastasis in the Microcirculation -- Chapter 12: Modelling Cell Adhesion and Extravasation in Microvascular system -- Chapter 13: Transport across the Blood-Brain Barrier -- Chapter 14: Blood-Brain Barrier Integrity and Clearance of Amyloid-β from the BBB -- Chapter 15: Mathematical Models of Cell Response Following Heating -- Chapter 16: Hypothermia Used in Medical Applications for Brain and Spinal Cord Injury Patients -- Chapter 17: Biomechanical Changes of Tympanic Membrane to Blast Waves.
520 _aThis book introduces the latest research in molecular, cellular, and tissue engineering of the vascular system. Topics covered include the roles of endothelial surface glycocalyx as a mechano-sensor and transducer for blood flow, a barrier to water and solute transport across the vascular wall and to the interaction between circulating cells and the vessel wall, the roles of nuclear envelope proteins and nuclear lamina in regulating vascular functions under blood flow-induced forces, and the roles of smooth muscle cells and extracellular components in arterial vasoconstriction. Other topics covered include non-surgical vascular interventions for coronary artery diseases, genesis and mechanisms of atherosclerotic plaque microcalcifications and human abdominal aortic aneurysms, experiments and modelling for red blood cell and tumor cell movement in microcirculation, transport across the blood-brain barrier and its role in Alzheimer's disease, mathematical models for cell survival after hyperthermia, application of hypothermia in enhancing treatment for brain and spinal cord injuries, and damage of eardrums due to blast waves. This is an ideal book for biomedical engineers and researchers, medical researchers, and students in biomedical engineering and medical sciences.
541 _fUABC ;
_cTemporal ;
_d01/01/2021-12/31/2023.
650 0 _aRegenerative medicine.
650 0 _aTissue engineering.
650 0 _aBiomedical engineering.
650 0 _aCardiology.
650 1 4 _aRegenerative Medicine/Tissue Engineering.
_0https://scigraph.springernature.com/ontologies/product-market-codes/L16080
650 2 4 _aBiomedical Engineering/Biotechnology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B24000
650 2 4 _aCardiology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/H33037
650 2 4 _aBiomedical Engineering and Bioengineering.
_0https://scigraph.springernature.com/ontologies/product-market-codes/T2700X
700 1 _aFu, Bingmei M.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aWright, Neil T.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783319964447
776 0 8 _iPrinted edition:
_z9783319964461
776 0 8 _iPrinted edition:
_z9783030071936
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v1097
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-96445-4
912 _aZDB-2-SBL
912 _aZDB-2-SXB
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