000 | 04947nam a22006135i 4500 | ||
---|---|---|---|
001 | 978-3-319-98839-9 | ||
003 | DE-He213 | ||
005 | 20210201191359.0 | ||
007 | cr nn 008mamaa | ||
008 | 180925s2018 gw | s |||| 0|eng d | ||
020 |
_a9783319988399 _9978-3-319-98839-9 |
||
050 | 4 | _aQH324.2-324.25 | |
072 | 7 |
_aPSA _2bicssc |
|
072 | 7 |
_aCOM014000 _2bisacsh |
|
072 | 7 |
_aPSA _2thema |
|
072 | 7 |
_aUB _2thema |
|
082 | 0 | 4 |
_a570.285 _223 |
100 | 1 |
_aMrozek, Dariusz. _eauthor. _0(orcid)0000-0001-6764-6656 _1https://orcid.org/0000-0001-6764-6656 _4aut _4http://id.loc.gov/vocabulary/relators/aut |
|
245 | 1 | 0 |
_aScalable Big Data Analytics for Protein Bioinformatics _h[electronic resource] : _bEfficient Computational Solutions for Protein Structures / _cby Dariusz Mrozek. |
250 | _a1st ed. 2018. | ||
264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2018. |
|
300 |
_aXXVI, 315 p. 151 illus., 110 illus. in color. _bonline resource. |
||
336 |
_atext _btxt _2rdacontent |
||
337 |
_acomputer _bc _2rdamedia |
||
338 |
_aonline resource _bcr _2rdacarrier |
||
347 |
_atext file _bPDF _2rda |
||
490 | 1 |
_aComputational Biology, _x1568-2684 ; _v28 |
|
500 | _aAcceso multiusuario | ||
505 | 0 | _aFormal Model of 3D Protein Structures for Functional Genomics, Comparative Bioinformatics, and Molecular Modeling -- Multithreaded PSS-SQL for Searching Databases of Secondary Structures -- GPU and CUDA for 3D Protein Structure Similarity Searching -- Cloud Computing for 3D Protein Structure Alignment -- General Discussion and Concluding Remarks. | |
520 | _aThis book presents a focus on proteins and their structures. The text describes various scalable solutions for protein structure similarity searching, carried out at main representation levels and for prediction of 3D structures of proteins. Emphasis is placed on techniques that can be used to accelerate similarity searches and protein structure modeling processes. The content of the book is divided into four parts. The first part provides background information on proteins and their representation levels, including a formal model of a 3D protein structure used in computational processes, and a brief overview of the technologies used in the solutions presented in the book. The second part of the book discusses Cloud services that are utilized in the development of scalable and reliable cloud applications for 3D protein structure similarity searching and protein structure prediction. The third part of the book shows the utilization of scalable Big Data computational frameworks, like Hadoop and Spark, in massive 3D protein structure alignments and identification of intrinsically disordered regions in protein structures. The fourth part of the book focuses on finding 3D protein structure similarities, accelerated with the use of GPUs and the use of multithreading and relational databases for efficient approximate searching on protein secondary structures. The book introduces advanced techniques and computational architectures that benefit from recent achievements in the field of computing and parallelism. Recent developments in computer science have allowed algorithms previously considered too time-consuming to now be efficiently used for applications in bioinformatics and the life sciences. Given its depth of coverage, the book will be of interest to researchers and software developers working in the fields of structural bioinformatics and biomedical databases. | ||
541 |
_fUABC ; _cTemporal ; _d01/01/2021-12/31/2023. |
||
650 | 0 | _aBioinformatics. | |
650 | 0 | _aComputer communication systems. | |
650 | 0 | _aProteins . | |
650 | 0 | _aBiomathematics. | |
650 | 1 | 4 |
_aComputational Biology/Bioinformatics. _0https://scigraph.springernature.com/ontologies/product-market-codes/I23050 |
650 | 2 | 4 |
_aComputer Communication Networks. _0https://scigraph.springernature.com/ontologies/product-market-codes/I13022 |
650 | 2 | 4 |
_aProtein Structure. _0https://scigraph.springernature.com/ontologies/product-market-codes/L14050 |
650 | 2 | 4 |
_aBioinformatics. _0https://scigraph.springernature.com/ontologies/product-market-codes/L15001 |
650 | 2 | 4 |
_aMathematical and Computational Biology. _0https://scigraph.springernature.com/ontologies/product-market-codes/M31000 |
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer Nature eBook | |
776 | 0 | 8 |
_iPrinted edition: _z9783319988382 |
776 | 0 | 8 |
_iPrinted edition: _z9783319988405 |
776 | 0 | 8 |
_iPrinted edition: _z9783030075385 |
830 | 0 |
_aComputational Biology, _x1568-2684 ; _v28 |
|
856 | 4 | 0 |
_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-98839-9 |
912 | _aZDB-2-SCS | ||
912 | _aZDB-2-SXCS | ||
942 | _cLIBRO_ELEC | ||
999 |
_c242816 _d242815 |