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020 _a9783319995465
_9978-3-319-99546-5
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082 0 4 _a615
_223
100 1 _aBöttger, Angelika.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
245 1 0 _aLessons on Caffeine, Cannabis & Co
_h[electronic resource] :
_bPlant-derived Drugs and their Interaction with Human Receptors /
_cby Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf.
250 _a1st ed. 2018.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2018.
300 _aX, 217 p. 69 illus., 50 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aLearning Materials in Biosciences,
_x2509-6125
500 _aAcceso multiusuario
505 0 _aIntroduction: Plant secondary metabolites and their general function in plants -- Historical and current perspective -- Medicinal use -- Recreational use -- General overview over biosynthesis pathways of plant secondary metabolites -- Drugs affecting GPCR: GPCRs in plants and animals -- Dopamine and 5-HT2A-serotonin receptors - Cocaine, mescaline, psilobin -- Opiate receptors - morphine, salvinorin A -- Cannabinoid receptors - THC -- Muscarinergic acetylcholin receptor - muscarin, atropine -- Adenosine receptor - caffeine -- Drugs affecting ion channels: Ligand and voltage activated channels -- Nicotinic acetylcholin receptor - Nicotine, Curare -- GABAA/C-receptor - Muscimol, thujone -- ionotropic Glycine receptor - Strychnine -- ionotropic Glutamate receptor - ibogtenic acid, kainic acid -- TRP channels - capsaicin, menthol, aconitine, resiniferatoxin -- Anti-cancer drugs acting on the cell cycle: Cell cycle in animals and plants -- Microtubuli - Colchicine, taxol, vinblastine, Podophyllotoxin (Lignan) -- Topoisomerase - camptothecin, etoposide -- G2/M phase arrest, apoptosis - curcubitacin, triptolide.
520 _aThis textbook provides a structured, easy to understand and thorough insight into the mode of function of plant secondary metabolites in plants and humans. It explains the biosynthesis and molecular action of nicotine, cannabis, caffeine and Co, describes the effects of these drugs on signal transduction at receptors and ion channels in animals, their relevance for human health and their potential for recreational use and abuse. It also offers a broad and comprehensive understanding on the role and function of these diverse molecules for the plants that make them. This textbook is written for master students and scientist in biochemistry and biology as well as for pharmaceutical and medical students. It will be a valuable study tool for teachers and students alike.
541 _fUABC ;
_cTemporal ;
_d01/01/2021-12/31/2023.
650 0 _aPharmacology.
650 0 _aPlant biochemistry.
650 0 _aScience education.
650 0 _aBiotechnology.
650 0 _aCancer research.
650 0 _aMolecular biology.
650 1 4 _aPharmacology/Toxicology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B21007
650 2 4 _aPlant Biochemistry.
_0https://scigraph.springernature.com/ontologies/product-market-codes/L14021
650 2 4 _aScience Education.
_0https://scigraph.springernature.com/ontologies/product-market-codes/O27000
650 2 4 _aBiotechnology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/C12002
650 2 4 _aCancer Research.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B11001
650 2 4 _aMolecular Medicine.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B1700X
700 1 _aVothknecht, Ute.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
700 1 _aBolle, Cordelia.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
700 1 _aWolf, Alexander.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783319995458
776 0 8 _iPrinted edition:
_z9783319995472
830 0 _aLearning Materials in Biosciences,
_x2509-6125
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-99546-5
912 _aZDB-2-SBL
912 _aZDB-2-SXB
942 _cLIBRO_ELEC
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