000 | 04914nam a22006615i 4500 | ||
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001 | 978-3-319-99546-5 | ||
003 | DE-He213 | ||
005 | 20210201191400.0 | ||
007 | cr nn 008mamaa | ||
008 | 181229s2018 gw | s |||| 0|eng d | ||
020 |
_a9783319995465 _9978-3-319-99546-5 |
||
050 | 4 | _aRM1-950 | |
072 | 7 |
_aMMG _2bicssc |
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_aMED071000 _2bisacsh |
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_aMKG _2thema |
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_a615 _223 |
100 | 1 |
_aBöttger, Angelika. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut |
|
245 | 1 | 0 |
_aLessons on Caffeine, Cannabis & Co _h[electronic resource] : _bPlant-derived Drugs and their Interaction with Human Receptors / _cby Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf. |
250 | _a1st ed. 2018. | ||
264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2018. |
|
300 |
_aX, 217 p. 69 illus., 50 illus. in color. _bonline resource. |
||
336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
||
347 |
_atext file _bPDF _2rda |
||
490 | 1 |
_aLearning Materials in Biosciences, _x2509-6125 |
|
500 | _aAcceso multiusuario | ||
505 | 0 | _aIntroduction: Plant secondary metabolites and their general function in plants -- Historical and current perspective -- Medicinal use -- Recreational use -- General overview over biosynthesis pathways of plant secondary metabolites -- Drugs affecting GPCR: GPCRs in plants and animals -- Dopamine and 5-HT2A-serotonin receptors - Cocaine, mescaline, psilobin -- Opiate receptors - morphine, salvinorin A -- Cannabinoid receptors - THC -- Muscarinergic acetylcholin receptor - muscarin, atropine -- Adenosine receptor - caffeine -- Drugs affecting ion channels: Ligand and voltage activated channels -- Nicotinic acetylcholin receptor - Nicotine, Curare -- GABAA/C-receptor - Muscimol, thujone -- ionotropic Glycine receptor - Strychnine -- ionotropic Glutamate receptor - ibogtenic acid, kainic acid -- TRP channels - capsaicin, menthol, aconitine, resiniferatoxin -- Anti-cancer drugs acting on the cell cycle: Cell cycle in animals and plants -- Microtubuli - Colchicine, taxol, vinblastine, Podophyllotoxin (Lignan) -- Topoisomerase - camptothecin, etoposide -- G2/M phase arrest, apoptosis - curcubitacin, triptolide. | |
520 | _aThis textbook provides a structured, easy to understand and thorough insight into the mode of function of plant secondary metabolites in plants and humans. It explains the biosynthesis and molecular action of nicotine, cannabis, caffeine and Co, describes the effects of these drugs on signal transduction at receptors and ion channels in animals, their relevance for human health and their potential for recreational use and abuse. It also offers a broad and comprehensive understanding on the role and function of these diverse molecules for the plants that make them. This textbook is written for master students and scientist in biochemistry and biology as well as for pharmaceutical and medical students. It will be a valuable study tool for teachers and students alike. | ||
541 |
_fUABC ; _cTemporal ; _d01/01/2021-12/31/2023. |
||
650 | 0 | _aPharmacology. | |
650 | 0 | _aPlant biochemistry. | |
650 | 0 | _aScience education. | |
650 | 0 | _aBiotechnology. | |
650 | 0 | _aCancer research. | |
650 | 0 | _aMolecular biology. | |
650 | 1 | 4 |
_aPharmacology/Toxicology. _0https://scigraph.springernature.com/ontologies/product-market-codes/B21007 |
650 | 2 | 4 |
_aPlant Biochemistry. _0https://scigraph.springernature.com/ontologies/product-market-codes/L14021 |
650 | 2 | 4 |
_aScience Education. _0https://scigraph.springernature.com/ontologies/product-market-codes/O27000 |
650 | 2 | 4 |
_aBiotechnology. _0https://scigraph.springernature.com/ontologies/product-market-codes/C12002 |
650 | 2 | 4 |
_aCancer Research. _0https://scigraph.springernature.com/ontologies/product-market-codes/B11001 |
650 | 2 | 4 |
_aMolecular Medicine. _0https://scigraph.springernature.com/ontologies/product-market-codes/B1700X |
700 | 1 |
_aVothknecht, Ute. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut |
|
700 | 1 |
_aBolle, Cordelia. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut |
|
700 | 1 |
_aWolf, Alexander. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer Nature eBook | |
776 | 0 | 8 |
_iPrinted edition: _z9783319995458 |
776 | 0 | 8 |
_iPrinted edition: _z9783319995472 |
830 | 0 |
_aLearning Materials in Biosciences, _x2509-6125 |
|
856 | 4 | 0 |
_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-99546-5 |
912 | _aZDB-2-SBL | ||
912 | _aZDB-2-SXB | ||
942 | _cLIBRO_ELEC | ||
999 |
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