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020 _a9783319926339
_9978-3-319-92633-9
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082 0 4 _a610
_223
100 1 _aRibatti, Domenico.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
245 1 0 _aJudah Folkman
_h[electronic resource] :
_bA Biography /
_cby Domenico Ribatti.
250 _a1st ed. 2018.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2018.
300 _aVIII, 124 p. 29 illus., 16 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
500 _aAcceso multiusuario
505 0 _aBiographic profile -- Development of assays to study angiogenesis -- Tumor angiogenesis -- The discovery of angiogenic factors -- Anti-angiogenesis -- Concluding remarks -- References -- Publications of Judah Folkman (2014-1956). Index.
520 _aThe aim if this book is to analyze the scientific biography of Judah Folkman, one of the most important scientist of the last century. More 50 years ago, Folkman found a revolutionary new way to think about cancer. Blood supply, Folkman hypothesized, was the key to tumor growth. Without new blood vessels, tumors simply did not thrive. In 1971, Folkman published his theory of angiogenesis in the "New England Journal of Medicine". Angiogenesis, the formation and recruitment of new blood vessels, is necessary for tumor growth. Critics of the theory were silenced over time as Folkman and his colleagues reported the first purified angiogenic molecule, the first angiogenesis inhibitor and proposed the concept of angiogenic disease. The mechanism of angiogenesis is now a worldwide field of investigation. Over the years, Folkman and a growing team of researchers have isolated the proteins and unraveled the processes that regulate angiogenesis. Meanwhile, a new generation of angiogenesis research has emerged as well, widening the field into new areas of human disease and deepening it to examine the underlying biological processes responsible for those diseases.
541 _fUABC ;
_cTemporal ;
_d01/01/2021-12/31/2023.
650 0 _aMedicine.
650 0 _aCell biology.
650 0 _aBiology-History.
650 1 4 _aBiomedicine, general.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B0000X
650 2 4 _aCell Biology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/L16008
650 2 4 _aHistory of Biology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/L31000
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783319926322
776 0 8 _iPrinted edition:
_z9783319926346
776 0 8 _iPrinted edition:
_z9783030064761
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-92633-9
912 _aZDB-2-SBL
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