000 | 03511nam a22005415i 4500 | ||
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001 | 978-3-319-92633-9 | ||
003 | DE-He213 | ||
005 | 20210201191446.0 | ||
007 | cr nn 008mamaa | ||
008 | 180622s2018 gw | s |||| 0|eng d | ||
020 |
_a9783319926339 _9978-3-319-92633-9 |
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_aRibatti, Domenico. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut |
|
245 | 1 | 0 |
_aJudah Folkman _h[electronic resource] : _bA Biography / _cby Domenico Ribatti. |
250 | _a1st ed. 2018. | ||
264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2018. |
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300 |
_aVIII, 124 p. 29 illus., 16 illus. in color. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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500 | _aAcceso multiusuario | ||
505 | 0 | _aBiographic profile -- Development of assays to study angiogenesis -- Tumor angiogenesis -- The discovery of angiogenic factors -- Anti-angiogenesis -- Concluding remarks -- References -- Publications of Judah Folkman (2014-1956). Index. | |
520 | _aThe aim if this book is to analyze the scientific biography of Judah Folkman, one of the most important scientist of the last century. More 50 years ago, Folkman found a revolutionary new way to think about cancer. Blood supply, Folkman hypothesized, was the key to tumor growth. Without new blood vessels, tumors simply did not thrive. In 1971, Folkman published his theory of angiogenesis in the "New England Journal of Medicine". Angiogenesis, the formation and recruitment of new blood vessels, is necessary for tumor growth. Critics of the theory were silenced over time as Folkman and his colleagues reported the first purified angiogenic molecule, the first angiogenesis inhibitor and proposed the concept of angiogenic disease. The mechanism of angiogenesis is now a worldwide field of investigation. Over the years, Folkman and a growing team of researchers have isolated the proteins and unraveled the processes that regulate angiogenesis. Meanwhile, a new generation of angiogenesis research has emerged as well, widening the field into new areas of human disease and deepening it to examine the underlying biological processes responsible for those diseases. | ||
541 |
_fUABC ; _cTemporal ; _d01/01/2021-12/31/2023. |
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650 | 0 | _aMedicine. | |
650 | 0 | _aCell biology. | |
650 | 0 | _aBiology-History. | |
650 | 1 | 4 |
_aBiomedicine, general. _0https://scigraph.springernature.com/ontologies/product-market-codes/B0000X |
650 | 2 | 4 |
_aCell Biology. _0https://scigraph.springernature.com/ontologies/product-market-codes/L16008 |
650 | 2 | 4 |
_aHistory of Biology. _0https://scigraph.springernature.com/ontologies/product-market-codes/L31000 |
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer Nature eBook | |
776 | 0 | 8 |
_iPrinted edition: _z9783319926322 |
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_iPrinted edition: _z9783319926346 |
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_iPrinted edition: _z9783030064761 |
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_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-92633-9 |
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