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_9978-3-319-72799-8
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072 7 _aMED052000
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072 7 _aMKFM
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082 0 4 _a616.9041
_223
245 1 0 _aUpdates on Clostridium difficile in Europe
_h[electronic resource] :
_bAdvances in Microbiology, Infectious Diseases and Public Health Volume 8 /
_cedited by Paola Mastrantonio, Maja Rupnik.
250 _a1st ed. 2018.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2018.
300 _aVIII, 261 p. 25 illus., 16 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Microbiology, Infectious Diseases and Public Health,
_x2365-2675 ;
_v1050
500 _aAcceso multiusuario
505 0 _aForeword (P. Mastrantonio and M. Rupnik) -- Economic burden of CDI in European countries (E. Reigadas and E. Bouza) -- The need for European surveillance of CDI(C. Wiuff, A.Lan Banks, F. Fitzpatrick, L. Cottom) -- Diagnostic guidance for C. difficile infections (M.J.T. Crobach,A.Baktash, N. Duszenko, E.J. Kuijper) -- Ribotypes and new virulent strains across Europe (J. Couturier, K. Davies, C. Gateau, F. Barbut) -- Comparative genomics of C. difficile strains (S. Janezic, J.R.Garneau, M. Monot) -- Cellular uptake and mode-of-action of Clostridium difficile toxins (P.Papatheodorou, H. Barth, N. Minton, K. Aktories) -- Clostridium difficile biofilm (C. Vuotto, G. Donelli, A. Buckley, C. Chilton) -- European practice for CDI treatment (F. Fitzpatrick, M. Skally, M. Brady, K. Burns, C. Rooney, M.H. Wilcox) -- Antibiotic resistances of Clostridium difficile (P. Spigaglia, P. Mastrantonio, F. Barbanti) -- Probiotics for prevention and treatment of Clostridium difficile infection (L. Valdés-Varela, M. Gueimonde, P. Ruas-Madiedo) -- Faecal microbiota transplantation as emerging treatment in European countries (M. Maida, J. McIlroy, G. Ianiro, G. Cammarota) -- Immunization strategies against Clostridium difficile (J.F. Bruxelle, S. Péchiné, A. Collignon) -- Non-human C. difficile reservoirs and sources: animals, food, environment (C. Rodriguez Diaz, C. Seyboldt , M. Rupnik) -- The ESCMIDStudy Group for Clostridium difficile: history, role and perspectives (J.E. Coia and E.J. Kuijper).
520 _aThis book outlines the currently available clinical, epidemiological and experimental data on Clostridium difficile infection (CDI) with special emphasis on studies and results achieved in Europe. The incidence and severity of CDI has increased significantly over the last decade, and the book explains why C. difficile, recently reclassified as Clostridioides difficile, remains a significant challenge, also from economic perspective, to health care systems all over the world. The different reservoirs of this ubiquitous microorganism are reviewed as well as the different factors contributing to its virulence, such as toxins and biofilm formation. The rapid evolution of antibiotic resistance is clearly a concern and in a specific way can influence the CDI epidemiology. Additionally, new emerging strains and comparative genomics studies are discussed for their relevance from epidemiological and evolutionary point of view. The book also gives an overview on diagnostics, therapy and surveillance, all of which are still challenging. Therefore, a closer look is taken on the effect of probiotics as an alternative to antibiotics, for prevention and treatment of CDI. Fecal transplantation from healthy donors, passive immunotherapies and vaccines for patients with recurrences are also discussed in dedicated chapters. The book closes with a summary of the history and the achievements of the European Society of Clinical Microbiology and Infectious Diseases Study Group for Clostridium difficile (ESGCD) written by the current and past presidents of the Society. It is the aim of this book to raise awareness on CDI and to disseminate updated information on its prevention, diagnosis and treatment.
541 _fUABC ;
_cTemporal ;
_d01/01/2021-12/31/2023.
650 0 _aMedical microbiology.
650 0 _aInfectious diseases.
650 0 _aMicrobiology.
650 1 4 _aMedical Microbiology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B16003
650 2 4 _aInfectious Diseases.
_0https://scigraph.springernature.com/ontologies/product-market-codes/H33096
650 2 4 _aMicrobiology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/L23004
700 1 _aMastrantonio, Paola.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aRupnik, Maja.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783319727981
776 0 8 _iPrinted edition:
_z9783319728001
776 0 8 _iPrinted edition:
_z9783319892108
830 0 _aAdvances in Microbiology, Infectious Diseases and Public Health,
_x2365-2675 ;
_v1050
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-72799-8
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