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020 _a9784431565147
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100 1 _aKameo, Yoshitaka.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
245 1 0 _aBone Adaptation
_h[electronic resource] :
_bIn Silico Approach /
_cby Yoshitaka Kameo, Ken-ichi Tsubota, Taiji Adachi.
250 _a1st ed. 2018.
264 1 _aTokyo :
_bSpringer Japan :
_bImprint: Springer,
_c2018.
300 _aXIV, 209 p. 93 illus., 24 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
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490 1 _aFrontiers of Biomechanics,
_x2199-8515 ;
_v2
500 _aAcceso multiusuario
505 0 _aOverview: In Silico Approaches to Understand Bone Adaptation -- Microscopic Fluid Flow Analysis in an Osteocyte Canaliculus -- Macroscopic Fluid Flow Analysis in a Poroelastic Trabecula -- Estimation of Bone Permeability for Poroelastic Analysis -- Modeling Trabecular Bone Adaptation Induced by Flow Stimuli to Osteocytes -- Effects of Local Bending Load on Trabecular Bone Adaptation -- Cancellous Bone Adaptation Predicted by Remodeling Simulations -- Trabecular Surface Remodeling toward Uniform Local Stress State -- Spatial and Temporal Regulation of Cancellous Bone Structure by Trabecular Surface Remodeling -- Comparison of Mechanical Quantities as Bone Remodeling Stimuli -- Trabecular Surface Remodeling Simulation of Cancellous Bone Using Image-Based Voxel Finite Element Models -- Functional Adaptation of Cancellous Bone in Human Proximal Femur -- 3D Trabecular Remodeling in Human Proximal Femur: Approach to Understanding Wolff's Law -- Trabecular Structural Changes in a Vertebral Body with a Fixation Screw.
520 _aThis book focuses on the systems biomechanics of bone remodeling that provide a multiscale platform for bone adaptation, spanning the cellular, tissue, and organ levels. The mathematical model explained in each section provides concrete examples of in silico approaches for bone adaptation. It will be immensely useful for readers interested in bone morphology and metabolism and will serve as an effective bridge connecting mechanics, cellular and molecular biology, and medical sciences. These in silico approaches towards exploring the mechanisms by which the functioning of dynamic living systems is established and maintained have potential for facilitating the efforts of graduate students and young researchers pioneering new frontiers of biomechanics.
541 _fUABC ;
_cTemporal ;
_d01/01/2021-12/31/2023.
650 0 _aBiomedical engineering.
650 0 _aOrthopedics.
650 0 _aBiomathematics.
650 0 _aBiophysics.
650 0 _aBiological physics.
650 0 _aRegenerative medicine.
650 0 _aTissue engineering.
650 0 _aComputer simulation.
650 1 4 _aBiomedical Engineering and Bioengineering.
_0https://scigraph.springernature.com/ontologies/product-market-codes/T2700X
650 2 4 _aOrthopedics.
_0https://scigraph.springernature.com/ontologies/product-market-codes/H45000
650 2 4 _aPhysiological, Cellular and Medical Topics.
_0https://scigraph.springernature.com/ontologies/product-market-codes/M31020
650 2 4 _aBiological and Medical Physics, Biophysics.
_0https://scigraph.springernature.com/ontologies/product-market-codes/P27008
650 2 4 _aRegenerative Medicine/Tissue Engineering.
_0https://scigraph.springernature.com/ontologies/product-market-codes/L16080
650 2 4 _aSimulation and Modeling.
_0https://scigraph.springernature.com/ontologies/product-market-codes/I19000
700 1 _aTsubota, Ken-ichi.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
700 1 _aAdachi, Taiji.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9784431565123
776 0 8 _iPrinted edition:
_z9784431565130
776 0 8 _iPrinted edition:
_z9784431568087
830 0 _aFrontiers of Biomechanics,
_x2199-8515 ;
_v2
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-4-431-56514-7
912 _aZDB-2-ENG
912 _aZDB-2-SXE
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