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001 978-3-319-70685-6
003 DE-He213
005 20210201191521.0
007 cr nn 008mamaa
008 171122s2018 gw | s |||| 0|eng d
020 _a9783319706856
_9978-3-319-70685-6
050 4 _aR856-857
050 4 _aHC79.E5
050 4 _aGE220
072 7 _aMQW
_2bicssc
072 7 _aTEC059000
_2bisacsh
072 7 _aMQW
_2thema
082 0 4 _a610.28
_223
245 1 0 _aCardiac Cell Culture Technologies
_h[electronic resource] :
_bMicrofluidic and On-Chip Systems /
_cedited by Zbigniew Brzozka, Elzbieta Jastrzebska.
250 _a1st ed. 2018.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2018.
300 _aXIX, 234 p. 58 illus., 57 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
500 _aAcceso multiusuario
505 0 _aIntroduction -- Microfluidic Systems -- Lab-on-a-chip Systems for Cellomics - Materials and Technology -- Organ-on-a-chip Systems -- Biological Bases of Cardiac Function and the Pro-Regenerative Potential of Stem Cells in the Treatment of Myocardial Disorder -- Pluripotent and Mesenchymal Stem Cells - Challenging Sources for Derivation of Myoblast -- Microfluidic Systems for Cardiac Cell Culture - Characterization -- Heart-on-a-chip Systems -- Cardiac Cell Culture Microtechnologies Based on Stem Cells.
520 _aMicrofluidic systems for cardiac cell culture are discussed based on tested cells and the methods of cardiac cell stimulation; The use of stem cell stimulation into cardiac cells in microfluidic systems is discussed in the context of electrical, biochemical, physical, and mechanical stimulations; Provides an overview of the measurements and data that can be extracted from on-chip systems for use in diagnostics, drug discovery and screening, and clinical therapy.  This book provides an introduction to the biological background of heart functioning and analyzes the various materials and technologies used for the development of microfluidic systems dedicated to cell culture, with an emphasis on cardiac cells. The authors describe the characterization of microfluidic systems for cardiac cell culture and center their discussion of the use of stem cell stimulation based on four different types: electrical, biochemical, physical, and mechanical. This book is appropriate for researchers focused on on-chip technologies and heart studies, students in bioengineering and microengineering courses, and a variety of professionals, such as biotechnologists, biomedical engineers, and clinicians working in the cardiac diseases field.
541 _fUABC ;
_cTemporal ;
_d01/01/2021-12/31/2023.
650 0 _aBiomedical engineering.
650 0 _aNanotechnology.
650 0 _aCardiology.
650 1 4 _aBiomedical Engineering and Bioengineering.
_0https://scigraph.springernature.com/ontologies/product-market-codes/T2700X
650 2 4 _aNanotechnology and Microengineering.
_0https://scigraph.springernature.com/ontologies/product-market-codes/T18000
650 2 4 _aBiomedical Engineering/Biotechnology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B24000
650 2 4 _aCardiology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/H33037
700 1 _aBrzozka, Zbigniew.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aJastrzebska, Elzbieta.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783319706849
776 0 8 _iPrinted edition:
_z9783319706863
776 0 8 _iPrinted edition:
_z9783319889795
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-70685-6
912 _aZDB-2-ENG
912 _aZDB-2-SXE
942 _cLIBRO_ELEC
999 _c244376
_d244375