000 | 04152nam a22006015i 4500 | ||
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001 | 978-3-031-30300-5 | ||
003 | DE-He213 | ||
005 | 20240207153623.0 | ||
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008 | 230622s2023 sz | s |||| 0|eng d | ||
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_a9783031303005 _9978-3-031-30300-5 |
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_aPSF _2bicssc |
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_aSCI049000 _2bisacsh |
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_a571.6 _223 |
245 | 1 | 0 |
_aHyaluronan _h[electronic resource] : _bStructure, Biology and Biotechnology / _cedited by Alberto Passi. |
250 | _a1st ed. 2023. | ||
264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2023. |
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300 |
_aX, 215 p. 39 illus., 34 illus. in color. _bonline resource. |
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_atext _btxt _2rdacontent |
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_acomputer _bc _2rdamedia |
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_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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490 | 1 |
_aBiology of Extracellular Matrix, _x2191-1959 ; _v14 |
|
500 | _aAcceso multiusuario | ||
505 | 0 | _aChapter 1: Biochemistry of hyaluronan synthesis -- Chapter 2: Update on hyaluronan in development -- Chapter 3: Long non-coding RNAs and epigenetic regulation of hyaluronan synthesis -- Chapter 4: The hyaluronan-rich zones of plasma membrane protrusions and extracellular vesicles -- Chapter 5: Hyaluronan in Kidney Fibrosis -- Chapter 6: Inter-α-inhibitor proteins: A review of structure and function -- Chapter 7: CD44: Does CD44v6 adversely impact the prognosis of cancer patients? -- Chapter 8: The pharmacokinetics and pharmacodynamics of 4-methylumbelliferone and its glucuronide metabolite in mice -- Chapter 9: The role of hyaluronan in skin wound healing -- Chapter 10: Sulfated hyaluronan: a novel player in cancer therapeutic and bioengineering approaches. | |
520 | _aThis book addresses the structural and biological properties of the extracellular matrix component and glycosaminoglycan polymer hyaluronan (or hyaluronic acid, HA). The book discusses various aspects of HA biology, e.g., HA synthesis and degradation, as well as the role of HA in embryogenesis, development, and cell maintenance. The reader will learn about the role of HA in different tissues as well as its biological activities triggered by the interaction with different HA receptors. A closer look is had at the involvement of HA in human pathologies such as cancer, kidney fibrosis and wound healing. Biotechnological and biomedical applications for HA such as scaffold generation and drug delivery, including the novel synthetic sulphated HA are explored. This work will appeal to a wide readership within the extracellular matrix and hyaluronan field. It can serve as an introduction to the field for junior scientists but can also help senior scientists to gain a broader view of the field beyond their area of specialization. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology. | ||
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_fUABC ; _cPerpetuidad |
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650 | 0 | _aCytology. | |
650 | 0 | _aDevelopmental biology. | |
650 | 0 | _aRegenerative medicine. | |
650 | 0 |
_aMedicine _xResearch. |
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650 | 0 |
_aBiology _xResearch. |
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650 | 1 | 4 | _aCell Biology. |
650 | 2 | 4 | _aDevelopmental Biology and Stem Cells. |
650 | 2 | 4 | _aRegenerative Medicine and Tissue Engineering. |
650 | 2 | 4 | _aBiomedical Research. |
700 | 1 |
_aPassi, Alberto. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt |
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710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer Nature eBook | |
776 | 0 | 8 |
_iPrinted edition: _z9783031302992 |
776 | 0 | 8 |
_iPrinted edition: _z9783031303012 |
776 | 0 | 8 |
_iPrinted edition: _z9783031303029 |
830 | 0 |
_aBiology of Extracellular Matrix, _x2191-1959 ; _v14 |
|
856 | 4 | 0 |
_zLibro electrónico _uhttp://libcon.rec.uabc.mx:2048/login?url=https://doi.org/10.1007/978-3-031-30300-5 |
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912 | _aZDB-2-SXB | ||
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