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020 _a9783031303005
_9978-3-031-30300-5
050 4 _aQH573-671
072 7 _aPSF
_2bicssc
072 7 _aSCI049000
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_2thema
082 0 4 _a571.6
_223
245 1 0 _aHyaluronan
_h[electronic resource] :
_bStructure, Biology and Biotechnology /
_cedited by Alberto Passi.
250 _a1st ed. 2023.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2023.
300 _aX, 215 p. 39 illus., 34 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aBiology of Extracellular Matrix,
_x2191-1959 ;
_v14
500 _aAcceso multiusuario
505 0 _aChapter 1: Biochemistry of hyaluronan synthesis -- Chapter 2: Update on hyaluronan in development -- Chapter 3: Long non-coding RNAs and epigenetic regulation of hyaluronan synthesis -- Chapter 4: The hyaluronan-rich zones of plasma membrane protrusions and extracellular vesicles -- Chapter 5: Hyaluronan in Kidney Fibrosis -- Chapter 6: Inter-α-inhibitor proteins: A review of structure and function -- Chapter 7: CD44: Does CD44v6 adversely impact the prognosis of cancer patients? -- Chapter 8: The pharmacokinetics and pharmacodynamics of 4-methylumbelliferone and its glucuronide metabolite in mice -- Chapter 9: The role of hyaluronan in skin wound healing -- Chapter 10: Sulfated hyaluronan: a novel player in cancer therapeutic and bioengineering approaches.
520 _aThis book addresses the structural and biological properties of the extracellular matrix component and glycosaminoglycan polymer hyaluronan (or hyaluronic acid, HA). The book discusses various aspects of HA biology, e.g., HA synthesis and degradation, as well as the role of HA in embryogenesis, development, and cell maintenance. The reader will learn about the role of HA in different tissues as well as its biological activities triggered by the interaction with different HA receptors. A closer look is had at the involvement of HA in human pathologies such as cancer, kidney fibrosis and wound healing. Biotechnological and biomedical applications for HA such as scaffold generation and drug delivery, including the novel synthetic sulphated HA are explored. This work will appeal to a wide readership within the extracellular matrix and hyaluronan field. It can serve as an introduction to the field for junior scientists but can also help senior scientists to gain a broader view of the field beyond their area of specialization. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
541 _fUABC ;
_cPerpetuidad
650 0 _aCytology.
650 0 _aDevelopmental biology.
650 0 _aRegenerative medicine.
650 0 _aMedicine
_xResearch.
650 0 _aBiology
_xResearch.
650 1 4 _aCell Biology.
650 2 4 _aDevelopmental Biology and Stem Cells.
650 2 4 _aRegenerative Medicine and Tissue Engineering.
650 2 4 _aBiomedical Research.
700 1 _aPassi, Alberto.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031302992
776 0 8 _iPrinted edition:
_z9783031303012
776 0 8 _iPrinted edition:
_z9783031303029
830 0 _aBiology of Extracellular Matrix,
_x2191-1959 ;
_v14
856 4 0 _zLibro electrónico
_uhttp://libcon.rec.uabc.mx:2048/login?url=https://doi.org/10.1007/978-3-031-30300-5
912 _aZDB-2-SBL
912 _aZDB-2-SXB
942 _cLIBRO_ELEC
999 _c261934
_d261933