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020 _a9783031358111
_9978-3-031-35811-1
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_2bicssc
072 7 _aSCI010000
_2bisacsh
072 7 _aTCB
_2thema
082 0 4 _a615.6
_223
245 1 0 _aPharmaceutical Formulations for Older Patients
_h[electronic resource] /
_cedited by Mine Orlu, Fang Liu.
250 _a1st ed. 2023.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2023.
300 _aXIII, 288 p. 63 illus., 61 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAAPS Advances in the Pharmaceutical Sciences Series,
_x2210-738X ;
_v51
500 _aAcceso multiusuario
505 0 _aPart 1: Patient-Centric Considerations.-Medicine Optimisation in Older -- Acceptability of drug formulations in older patients and effect on patient adherence -- Geriatric biopharmaceutics -- Excipient safety in older adults -- Part 2: Pharmaceutical Formulations Development for older Patients -- Oral and oromucosal formulation development and in vitro characterisation - patient-centric approaches for older adults -- Pulmonary drug delivery systems for older people -- Transdermal drug delivery systems for older patients -- Part 3 :Advanced Drug Delivery Systems for Older Patients -- Advanced oral drug delivery systems for older patients -- The ageing microbiome, pharmaceutical considerations and therapeutic opportunities -- Application of 3D printing in geriatric medicines, -- Application of electrospraying and advanced fabrication methods in geriatric medicines -- Vaccine development for older patients.
520 _aPharmaceutical formulation design affects patient acceptability/adherence and pharmacokinetics of the drug. This is particularly important for older patients because of the physiological changes due to ageing and clinical/social circumstances related to medicine taking. This book provides a comprehensive review in the design of formulations to meet the needs of older patients. An overview of the key clinical, social and pharmaceutical factors affecting medication optimization, safety and acceptability in older adults is included, followed by patient-centric considerations including regulatory requirements, dosage form design and human factor studies. Advanced pharmaceutical technologies are discussed for their potential use in older adults such as 3D printing, long-acting oral formulations and novel vaccine technologies. The unique focus of the book will be of interest to pharmaceutical scientists in both industry and academia in searching for better formulations for older patients.
541 _fUABC ;
_cPerpetuidad
650 0 _aDrug delivery systems.
650 0 _aPharmaceutical chemistry.
650 0 _aPharmacology.
650 0 _aMedicine
_xResearch.
650 0 _aBiology
_xResearch.
650 1 4 _aDrug Delivery.
650 2 4 _aPharmaceutics.
650 2 4 _aPharmacology.
650 2 4 _aBiomedical Research.
700 1 _aOrlu, Mine.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aLiu, Fang.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031358104
776 0 8 _iPrinted edition:
_z9783031358128
776 0 8 _iPrinted edition:
_z9783031358135
830 0 _aAAPS Advances in the Pharmaceutical Sciences Series,
_x2210-738X ;
_v51
856 4 0 _zLibro electrónico
_uhttp://libcon.rec.uabc.mx:2048/login?url=https://doi.org/10.1007/978-3-031-35811-1
912 _aZDB-2-SBL
912 _aZDB-2-SXB
942 _cLIBRO_ELEC
999 _c263225
_d263224