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082 0 4 _a616.9041
_223
245 1 0 _aUpdates on Clostridioides difficile in Europe
_h[electronic resource] :
_bAdvances in Microbiology, Infectious Diseases and Public Health Volume 18 /
_cedited by Paola Mastrantonio, Maja Rupnik.
250 _a2nd ed. 2024.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2024.
300 _aX, 362 p. 28 illus., 25 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Microbiology, Infectious Diseases and Public Health,
_x2365-2683 ;
_v1435
505 0 _aEconomic burden of Clostridioides difficile infection in European countries -- The need for European surveillance of CDI.-Diagnostic guidance for C. difficile infections -- European practice for CDI treatment -- Faecal microbiota transplantation as emerging treatment in European countries 2.0 -- Probiotics for prevention and treatment of Clostridioides difficile infection -- Immunization strategies against Clostridioides difficile -- Ribotypes and new virulent strains across Europe -- Antibiotic resistances of Clostridioides difficile -- Comparative genomics of Clostridioides difficile -- An updated view on the cellular uptake and mode-of-action of Clostridioides difficile toxins -- Clostridioides difficile biofilm -- Clostridioides difficile sporulation -- Membrane vesicles of C.difficile and other Clostridial species -- Non-human C.difficile reservoirs and sources: animals,food, environment -- The ESCMID Study Group for Clostridioides difficile : history, role and perspectives.
520 _aThis fully updated second edition outlines the currently available clinical, epidemiological and experimental data on Clostridioides difficile infections(CDI) with special emphasis on studies and results achieved in Europe. The incidence and severity of CDI has increased significantly over the last decade, and the book explains why C. difficile, recently reclassified as Clostridioides difficile, remains a significant challenge, also from economic perspective, to health care systems all over the world. The different reservoirs of this ubiquitous microorganism are reviewed as well as the different factors contributing to its virulence, such as toxins and biofilm formation. The rapid evolution of antibiotic resistance is clearly a concern and in a specific way can influence the CDI epidemiology. Additionally, new emerging strains and comparative genomics studies are taken into consideration for their relevance from epidemiological and evolutionary point of view. The book also gives an overview on diagnostics, therapy and surveillance, all of which are still challenging. Therefore, a closer look is taken on the effect of probiotics as an alternative to antibiotics, for prevention and treatment of CDI. Fecal transplantation from healthy donors, passive immunotherapies and vaccines for patients with recurrences are also discussed in dedicated chapters. New topics included sporulation and membrane vesicles in C. difficile. The book closes with a summary of the history and the achievements of the European Society of Clinical Microbiology and Infectious Diseases Study Group for Clostridium difficile (ESGCD) written by the current and past presidents of the Society. It is the aim of this book to raise awareness on CDI and to disseminate updated information on its prevention, diagnosis and treatment.
541 _fUABC ;
_cPerpetuidad
650 0 _aMedical microbiology.
650 0 _aDiseases.
650 0 _aMicrobiology.
650 1 4 _aMedical Microbiology.
650 2 4 _aDiseases.
650 2 4 _aMicrobiology.
700 1 _aMastrantonio, Paola.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aRupnik, Maja.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031421075
776 0 8 _iPrinted edition:
_z9783031421099
776 0 8 _iPrinted edition:
_z9783031421105
830 0 _aAdvances in Microbiology, Infectious Diseases and Public Health,
_x2365-2683 ;
_v1435
856 4 0 _zLibro electrónico
_uhttp://libcon.rec.uabc.mx:2048/login?url=https://doi.org/10.1007/978-3-031-42108-2
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