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001 978-3-031-30023-3
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020 _a9783031300233
_9978-3-031-30023-3
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072 7 _aSCI013040
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082 0 4 _a615.19
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245 1 0 _aPharmaceutical Biotechnology
_h[electronic resource] :
_bFundamentals and Applications /
_cedited by Daan J. A. Crommelin, Robert D. Sindelar, Bernd Meibohm.
250 _a6th ed. 2024.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2024.
300 _aXXV, 682 p. 259 illus., 245 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aMolecular Biotechnology -- Biophysical and biochemical analysis of recombinant proteins -- Production and downstream processing of biotech products -- Formulation of biotech products, including biopharmaceutical considerations -- Pharmacokinetics and pharmacodynamics of peptide and protein drugs -- Immunogenicity of pharmaceutical proteins -- General considerations of monoclonal antibodies from structure to therapeutic application -- Genomics, Other "Omics" Technologies, Personalized Medicine and Additional Biotechnology-Related Techniques -- Dispensing biotechnology products: handling, professional education and product information -- Economic considerations in medical biotechnology -- Regulatory framework for biosimilars -- Vaccines -- Oligonucleotides and siRNA -- Gene therapy -- Stem cell technology -- Therapeutic Applications.-Endocrinology -- Insulin -- Follicle-stimulating hormone -- Growth hormone -- Cardiovascular and Respiratory Applications -- Recombinant coagulation factors and thrombolytics -- Recombinant human deoxyribonuclease -- Oncology -- Monoclonal antibodies in oncology -- Hematopoetic growth factors -- Inflammation and Immunemodulation -- Monoclonal antibodies in transplantation -- Monoclonal antibodies and antibody-based therapeutics in anti-inflammatory therapy -- Interferons and interleukins -- Anti-infectious diseases -- Monoclonal antibodies -- Enzyme replacement therapy.
520 _aThis introductory text explains both the basic science, production, quality, dosage forms, administration, economic and regulatory aspects and the clinical applications of biotechnology-derived pharmaceuticals. It serves as a complete one-stop source for undergraduate/graduate pharmacists and pharmaceutical science students. An additional important audience are pharmaceutical scientists in industry and academia, particularly those who have not received formal training in pharmaceutical biotechnology and are inexperienced in this field. The rapid growth and advances in the field made it necessary to revise this textbook in order to continue providing up-to-date information and introduce readers to cutting edge knowledge and technology of this field. This Sixth Edition completely updates the previous edition and includes additional coverage on new approaches such as oligonucleotides, siRNA, mRNA, gene therapy, cell therapies, monoclonal antibodies and vaccines. With more than 3-million-chapter downloads, the fifth edition of the textbook has achieved widespread distribution as a key educational resource for the field of pharmaceutical biotechnology.
541 _fUABC ;
_cPerpetuidad
650 0 _aPharmaceutical chemistry.
650 0 _aBiotechnology.
650 0 _aPharmacology.
650 0 _aMedicine
_xResearch.
650 0 _aBiology
_xResearch.
650 0 _aDrug delivery systems.
650 0 _aBiologicals.
650 0 _aBiopharmaceutics.
650 1 4 _aPharmaceutics.
650 2 4 _aBiotechnology.
650 2 4 _aPharmacology.
650 2 4 _aBiomedical Research.
650 2 4 _aDrug Delivery.
650 2 4 _aBiologics.
700 1 _aCrommelin, Daan J. A.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aSindelar, Robert D.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aMeibohm, Bernd.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031300226
776 0 8 _iPrinted edition:
_z9783031300240
776 0 8 _iPrinted edition:
_z9783031303272
856 4 0 _zLibro electrónico
_uhttp://libcon.rec.uabc.mx:2048/login?url=https://doi.org/10.1007/978-3-031-30023-3
912 _aZDB-2-SBL
912 _aZDB-2-SXB
942 _cLIBRO_ELEC
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