000 03416nam a22006495i 4500
001 978-3-031-69162-1
003 DE-He213
005 20250516160149.0
007 cr nn 008mamaa
008 241015s2024 sz | s |||| 0|eng d
020 _a9783031691621
_9978-3-031-69162-1
050 4 _aR850.A1-854
050 4 _aQH315-320
072 7 _aMBGR
_2bicssc
072 7 _aMED106000
_2bisacsh
072 7 _aMBGR
_2thema
082 0 4 _a610.72
_223
245 1 0 _aStructure-Based Drug Design
_h[electronic resource] /
_cedited by Marcelo A. Marti, Adrian Gustavo Turjanski, Dario Fernández Do Porto.
250 _a1st ed. 2024.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2024.
300 _aIX, 256 p. 80 illus., 70 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aComputer-Aided Drug Discovery and Design,
_x2730-5465 ;
_v2
505 0 _aPrioritizing Drug Targets in Pathogenic Bacteria by Harnessing Structural Biology, Metabolic Analysis, and Omics Data Integration -- Regulatory small RNAs as antimicrobial drug targets -- Riboswitches as antimicrobial targets -- Pre-selection of compounds for lead identification in virtual screening campaigns -- Docking and Bias Docking -- Molecular Dynamics and its Significance in Drug Discovery -- Deep Learning Strategies for Enhanced Molecular Docking and Virtual Screening -- Integrating computational approaches from non-synonymous sequence variations to molecular structure for drug repositioning targeting the SARS-CoV-2 Spike protein.
520 _aThis volume focuses on target-oriented approximations to drug discovery, including target selection, binding pocket detection, and current uses and variants of molecular dynamics and molecular docking. The primary audience is PhD and graduates working in the field of molecular biology, structural biology, pharmaceutical sciences.
541 _fUABC ;
_cPerpetuidad
650 0 _aMedicine
_xResearch.
650 0 _aBiology
_xResearch.
650 0 _aPharmacology.
650 0 _aDrugs
_xDesign.
650 0 _aPharmaceutical chemistry.
650 0 _aPharmacy.
650 1 4 _aBiomedical Research.
650 2 4 _aPharmacology.
650 2 4 _aStructure-Based Drug Design.
650 2 4 _aPharmaceutics.
650 2 4 _aPharmacy.
700 1 _aMarti, Marcelo A.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aTurjanski, Adrian Gustavo.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aFernández Do Porto, Dario.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031691614
776 0 8 _iPrinted edition:
_z9783031691638
776 0 8 _iPrinted edition:
_z9783031691645
830 0 _aComputer-Aided Drug Discovery and Design,
_x2730-5465 ;
_v2
856 4 0 _zLibro electrónico
_uhttp://libcon.rec.uabc.mx:2048/login?url=https://doi.org/10.1007/978-3-031-69162-1
912 _aZDB-2-SBL
912 _aZDB-2-SXB
942 _cLIBRO_ELEC
999 _c276659
_d276658