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020 _a9783031748424
_9978-3-031-74842-4
050 4 _aRC261-271
050 4 _aQH588.S83
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
072 7 _aMJCL
_2thema
082 0 4 _a571.978
_223
082 0 4 _a616.02774
_223
245 1 0 _aCancer Stem Cells and Cancer Therapy
_h[electronic resource] /
_cedited by Rasime Kalkan.
250 _a1st ed. 2024.
264 1 _aCham :
_bSpringer Nature Switzerland :
_bImprint: Springer,
_c2024.
300 _aXXI, 376 p. 37 illus., 36 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aStem Cell Biology and Regenerative Medicine,
_x2196-8993 ;
_v76
505 0 _aCharacteristics of Stem Cells and Cancer Stem Cells -- Stem Cell Niche -- Hypoxia, Stem Cells and Cancer Stem Cells -- Altered Wnt Pathway and Cancer Stem Cells -- Altered PI3K/AKT/MTOR Pathway and Cancer Stem Cells -- Altered NOTCH Pathway and Cancer Stem Cells -- Cancer Stem Cells And Immunity -- Cancer Stem Cells and Tumor MicrobiomeCancer Stem Cells in the Hematopoietic SystemUnderstanding The Role Of Cancer Stem Cells In Brain Tumor Pathogenesis -- Cancer Stem Cells in Lung Cancer, A Novel FrontierCancer Stem Cells in Gastrointestinal CancersCancer Stem Cells in Breast Cancer -- The Role Of CAR-T Cells in Targeting Cancer Stem Cells.
520 _aThis book explores the importance of cancer stem cells and their usage. Cancer is a serious health issue that affects people all over the world. Numerous studies back up the theory that stem cells play a role in cancer development. The population of cancer stem cells (CSCs) exhibits tumorigenic potential and possesses stem cell-specific markers and characteristics, such as self-renewal/proliferation and differentiation. Carcinogenesis may be significantly influenced by CSCs. Currently, treatment techniques concentrate on eliminating the CSC subpopulation using various methods, such as bypassing CSC resistance mechanisms or focussing on important biochemical pathways that govern these cells. New approaches are still required even though the negative effects of current treatment approaches are minimal. The information that has been gathered on the stem cell theory of carcinogenesis, the impact of dysregulated stem cell self-renewal on cancer transformation, and the functions of CSCs in cancer treatment are presented in this book. We also discuss how a deeper comprehension of the biology, behaviour, and environment of CSCs can advance the use of these cells in cancer therapy and lead to the development of more potent cancer treatment plans. Given its scope, Cancer Stem Cells and Cancer Therapy is an indispensable resource not only for researchers working in the field of human biology and cancer research but also for advanced students seeking an introduction to cancer stem cells and their therapeutic usage.
541 _fUABC ;
_cPerpetuidad
650 0 _aCancer.
650 0 _aStem cells.
650 0 _aCancer
_xTreatment.
650 0 _aTumors
_xImmunological aspects.
650 0 _aImmunotherapy.
650 1 4 _aCancer Stem Cells.
650 2 4 _aCancer Therapy.
650 2 4 _aCancer Biology.
650 2 4 _aTumour Immunology.
650 2 4 _aImmunotherapy.
700 1 _aKalkan, Rasime.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031748417
776 0 8 _iPrinted edition:
_z9783031748431
776 0 8 _iPrinted edition:
_z9783031748448
830 0 _aStem Cell Biology and Regenerative Medicine,
_x2196-8993 ;
_v76
856 4 0 _zLibro electrónico
_uhttp://libcon.rec.uabc.mx:2048/login?url=https://doi.org/10.1007/978-3-031-74842-4
912 _aZDB-2-SBL
912 _aZDB-2-SXB
942 _cLIBRO_ELEC
999 _c277106
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